50-168-5202

PGR Mouse anti-Human, Clone: UMAB135, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5202-Each-of-1 In Stock ₹ 54,529.10

50-168-5202 - Each of 1

₹ 54,529.10

In Stock

Quantity

1

Base Price: ₹ 54,529.10

GST (18%): ₹ 9,815.238

Total Price: ₹ 64,344.338

Antigen

PGR

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PGR

Gene Alias

NR3C3, PR

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5241

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

UMAB135

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P06401

Gene Symbols

PGR

Immunogen

Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • The progesterone receptor (PR) is a member of the steroid family of nuclear receptors
  • The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintece of pregcy
  • PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites
  • PR-B is the transcriptionally active form and is responsible for activating genes for the maintece of the endometrium, maintece of pregcy, and inhibition of ovulation
  • PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus
  • This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity
  • In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins
  • Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription
  • A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5202

--


Antigen:
PGR

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
NR3C3, PR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB135

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-5205

--


Antigen:
PGR

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
NR3C3, PR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB136

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5206

--


Antigen:
PGR

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
NR3C3, PR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB137

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-5208

--


Antigen:
DOCK2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
DOCK2

Gene Alias:
IMD40

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1794

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB142

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q92608

Gene Symbols:
DOCK2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1544-1830 of human DOCK2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a