50-168-5353

PDCD1 Mouse anti-Human, Mouse, Clone: UMAB222, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5353-Each-of-1 In Stock ₹ 54,529.10

50-168-5353 - Each of 1

₹ 54,529.10

In Stock

Quantity

1

Base Price: ₹ 54,529.10

GST (18%): ₹ 9,815.238

Total Price: ₹ 64,344.338

Antigen

PDCD1

Classification

Monoclonal

Concentration

0.5-1.0 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q02242, Q15116

Gene Symbols

Pdcd1

Immunogen

Full length human recombit protein of human PDCD1 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

UMAB222

Conjugate

Unconjugated

Gene

PDCD1

Gene Alias

CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18566, 5133

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • PD-1 (Programmed Cell Death Protein 1, PCDP-1, CD279) is a cell surface receptor approximately 273-290 amino acids in length that inhibits cell-mediated immune responses initiated by T lymphocytes
  • PD-1 can bind two different but related ligands, PDL-1 and PDL-2
  • Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as lipopolysaccharide (LPS) associated with bacteria or pathogens
  • Evidence for this is seen in PD1-null mice who exhibit hyper-activated immune systems and autoimmune diseases
  • Further, expression of this gene in mice is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis
  • Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure.

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Img

OriGene

50-168-5353

--


Antigen:
PDCD1

Classification:
Monoclonal

Concentration:
0.5-1.0 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q02242, Q15116

Gene Symbols:
Pdcd1

Immunogen:
Full length human recombit protein of human PDCD1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
UMAB222

Conjugate:
Unconjugated

Gene:
PDCD1

Gene Alias:
CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18566, 5133

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-5354

--


Antigen:
PDCD1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q02242, Q15116

Gene Symbols:
Pdcd1

Immunogen:
Full length human recombit protein of human PDCD1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Peptide Array

Clone:
UMAB222

Conjugate:
Unconjugated

Gene:
PDCD1

Gene Alias:
CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18566, 5133

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

OriGene

50-168-5355

--


Antigen:
PD-L2 (PDCD1LG2)

Classification:
Monoclonal

Concentration:
0.5-1.0 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9BQ51

Gene Symbols:
PDCD1LG2

Immunogen:
Full length human recombit protein of human PDCD1LG2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
UMAB223

Conjugate:
Unconjugated

Gene:
PDCD1LG2

Gene Alias:
B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80380

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-5356

--


Antigen:
PD-L2 (PDCD1LG2)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9BQ51

Gene Symbols:
PDCD1LG2

Immunogen:
Full length human recombit protein of human PDCD1LG2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Peptide Array

Clone:
UMAB223

Conjugate:
Unconjugated

Gene:
PDCD1LG2

Gene Alias:
B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80380

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized