50-168-5489

PGR Mouse anti-Human, Clone: UMAB136, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5489-Each-of-1 In Stock ₹ 22,040.26

50-168-5489 - Each of 1

₹ 22,040.26

In Stock

Quantity

1

Base Price: ₹ 22,040.26

GST (18%): ₹ 3,967.247

Total Price: ₹ 26,007.507

Antigen

PGR

Classification

Monoclonal

Concentration

0.5-1.0 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P06401

Gene Symbols

PGR

Immunogen

Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

UMAB136

Conjugate

Unconjugated

Gene

PGR

Gene Alias

NR3C3, PR

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5241

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

OriGene

50-168-5490

--

Img

OriGene

50-168-5488

--

Img

OriGene

50-168-5513

--

Img

OriGene

50-168-5495

--

Img

OriGene

50-168-5610

--

Img

OriGene

50-168-5509

--

Img

OriGene

50-168-5607

--

Img

OriGene

50-168-5449

--

Description

  • The progesterone receptor (PR) is a member of the steroid family of nuclear receptors
  • The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintece of pregcy
  • PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites
  • PR-B is the transcriptionally active form and is responsible for activating genes for the maintece of the endometrium, maintece of pregcy, and inhibition of ovulation
  • PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus
  • This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity
  • In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins
  • Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription
  • A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5489

--


Antigen:
PGR

Classification:
Monoclonal

Concentration:
0.5-1.0 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB136

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
NR3C3, PR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-5490

--


Antigen:
PGR

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB137

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
NR3C3, PR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-5493

--


Antigen:
HMBS

Classification:
Monoclonal

Concentration:
0.5-1.0 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08397

Gene Symbols:
HMBS

Immunogen:
Full length human recombit protein of human HMBS produced in HEK293T cell.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB144

Conjugate:
Unconjugated

Gene:
HMBS

Gene Alias:
PBG-D, PBGD, PORC, UPS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3145

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-5495

--


Antigen:
TOP2A

Classification:
Monoclonal

Concentration:
0.5-1.0 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P11388

Gene Symbols:
TOP2A

Immunogen:
Human recombit protein fragment corresponding to amino acids 1100-1531 of human TOP2A produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB146

Conjugate:
Unconjugated

Gene:
TOP2A

Gene Alias:
TOP2, TP2A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7153

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid