50-168-5597

MSH2 Mouse anti-Human, Clone: UMAB259, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5597-Each-of-1 In Stock ₹ 22,040.26

50-168-5597 - Each of 1

₹ 22,040.26

In Stock

Quantity

1

Base Price: ₹ 22,040.26

GST (18%): ₹ 3,967.247

Total Price: ₹ 26,007.507

Antigen

MSH2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

MSH2

Gene Alias

COCA1, FCC1, HNPCC, HNPCC1, LCFS2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4436

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

UMAB259

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P43246

Gene Symbols

MSH2

Immunogen

Human recombit protein fragment corresponding to amino acids 1-304 of human MSH2 produced in E.coli.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Germline mutations in human mismatch repair genes (hMSH2, hMSH6, hMLH1, hPMS2) account for majority of the hereditary non-polyposis colorectal carcinoma (HPNCC)
  • CpG dinucleotides in the hMSH2 and hMLH1 genes are hotspots for HNPCC mutations
  • These mutations cause a mismatch repair deficiency resulting in a mutator phenotype where the replication errors are not repaired
  • Microsatellites/simple repeatative sequences are prone to this type of replication errors and instability of these microsatellites correlates with the occurance of HPNCC
  • hMSH2 binds to another MutS homolog protein GTBP to form a heterodimeric complex called hMutSbeta, which binds to insertion/deletion loops in DNA.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5597

--


Antigen:
MSH2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MSH2

Gene Alias:
COCA1, FCC1, HNPCC, HNPCC1, LCFS2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4436

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB259

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P43246

Gene Symbols:
MSH2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-304 of human MSH2 produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-5601

--


Antigen:
EZH2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
EZH2

Gene Alias:
ENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2146

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB264

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q15910

Gene Symbols:
EZH2

Immunogen:
Human recombit protein fragment corresponding to amino acids 182-431 of human EZH2 produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5602

--


Antigen:
CDX2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CDX2

Gene Alias:
CDX-3, CDX2/AS, CDX3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1045

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB265

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q99626

Gene Symbols:
CDX2

Immunogen:
Full length human recombit protein of human CDX2 produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-5605

--


Antigen:
SDHB

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SDHB

Gene Alias:
CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6390

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB268

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P21912

Gene Symbols:
SDHB

Immunogen:
Full length human recombit protein of human SDHB produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1