50-172-6133
SMAD4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6133-Each-of-1 | In Stock | ₹ 42,443.75 |
50-172-6133 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
SMAD4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMAD4
Gene Alias
DPC4, hSMAD4, JIP, MAD homolog 4, MADH4, Mothers against DPP homolog 4, SMAD 4, SMAD family member 4, SMAD4
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17128, 4089
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.24 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
P97471, Q13485
Gene Symbols
Smad4
Immunogen
SMAD4 Fusion Protein Ag0299
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is a rabbit polyclonal antibody raised against an internal region of human SMAD4
- Smad4 is encoded by the Smad4 gene that is located on chromosome 18 in humans
- Smad4 is also known as Smad family member 4, Sma- and Mad-related protein 4 or Mothers against decapentaplegic (MAD) homolog 4
- Smad4 contains N-terminal MH1 (MAD homology 1) and C-terminal MH2 (MAD homology 2) globular domains that are involved in DNA binding and protein interactions respectively
- Binding of the TGF-beta superfamily of ligands that includes Transforming Growth Factor -beta (TGF-beta) and bone morphogenetic protein (BMP) to its cognate receptor allows phosphorylation of Smad 1, 2, 3, 5 and 8 (R-Smad, Receptor Smad)
- This signals for heterotrimerization with Smad4 (co-Smad, co-mediator Smad) and translocation of the complex to the nucleus
- Inhibitory or antagonistic Smad (I-Smad) that includes Smad 6 and 7, interact with activated R-Smads and attenuate the signaling pathway
- Smad4 acts as a tumor suppressor protein by transcriptionally regulating its target genes such as Cyclin D1 (downregulation) and collagen (upregulation) that inhibit cell proliferation
- Dephosphorylation regulates nuclear export and nucleocytoplasmic dynamics of Smads.
Compare Similar Items
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Antigen: SMAD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD4
Gene Alias: DPC4, hSMAD4, JIP, MAD homolog 4, MADH4, Mothers against DPP homolog 4, SMAD 4, SMAD family member 4, SMAD4
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17128, 4089
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.24 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P97471, Q13485
Gene Symbols: Smad4
Immunogen: SMAD4 Fusion Protein Ag0299
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SMAD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD4
Gene Alias:
DPC4, hSMAD4, JIP, MAD homolog 4, MADH4, Mothers against DPP homolog 4, SMAD 4, SMAD family member 4, SMAD4
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17128, 4089
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.24 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P97471, Q13485
Gene Symbols:
Smad4
Immunogen:
SMAD4 Fusion Protein Ag0299
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ARL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ARL2
Gene Alias: ADP ribosylation factor like 2, ARFL2, ARL2
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 402, 56327, 65142
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: O08697, P36404, Q9D0J4
Gene Symbols: ARL2
Immunogen: ARL2 Fusion Protein Ag0334
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ARL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ARL2
Gene Alias:
ADP ribosylation factor like 2, ARFL2, ARL2
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
402, 56327, 65142
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
O08697, P36404, Q9D0J4
Gene Symbols:
ARL2
Immunogen:
ARL2 Fusion Protein Ag0334
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Transgelin 2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TAGLN2
Gene Alias: SM22 beta, SM22beta, TAGLN2, Transgelin 2
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21346, 8407
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.21 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P37802, Q9WVA4
Gene Symbols: TAGLN2
Immunogen: Transgelin 2 Fusion Protein Ag0337
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Transgelin 2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TAGLN2
Gene Alias:
SM22 beta, SM22beta, TAGLN2, Transgelin 2
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21346, 8407
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.21 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P37802, Q9WVA4
Gene Symbols:
TAGLN2
Immunogen:
Transgelin 2 Fusion Protein Ag0337
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: S100A11
Classification: Polyclonal
Conjugate: Unconjugated
Gene: S100A11
Gene Alias: Calgizzarin, MLN 70, MLN70, Protein S100 A11, Protein S100 C, S100A11, S100C
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20195, 445415, 6282
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.46 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P31949, P50543, Q6B345
Gene Symbols: S100A11
Immunogen: S100A11 Fusion Protein Ag0343
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
S100A11
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
S100A11
Gene Alias:
Calgizzarin, MLN 70, MLN70, Protein S100 A11, Protein S100 C, S100A11, S100C
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20195, 445415, 6282
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.46 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P31949, P50543, Q6B345
Gene Symbols:
S100A11
Immunogen:
S100A11 Fusion Protein Ag0343
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG