50-172-6212

APEX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-172-6212-Each-of-1 In Stock ₹ 42,443.75

50-172-6212 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

APEX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APEX1

Gene Alias

AP endonuclease 1, APE, APE1, APE1,APEX1, APEN, APEX, APEX nuclease, APEX1, APX, HAP1, Protein REF 1, REF1

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11792, 328, 79116

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.37 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P27695, P28352, P43138

Gene Symbols

APEX1

Immunogen

APEX1 Fusion Protein Ag0397

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • 10323-1-AP is a rabbit polyclonal antibody raised against a fusion protein corresponding to an internal region of human APEX1
  • Mammalian apurinic/apyrimidinic endonuclease (APE/ref-1) is a multifunctional, bipartite enzyme that plays an important role in numerous, cellular functions
  • APE is responsible for repairing abasic sites in DNA and in regulating the redox state of other proteins that play roles in oxidative signaling, transcription factor regulation (Fos, Jun, NF-kB, Myb, HIF-1 alpha, CREB, Pax), cell cycle control (p53), and apoptosis
  • The most common form of DNA damage is the creation of abasic sites which are brought about through spontaneous loss or oxidative DNA damage, through chemically initiated hydrolysis (chemotherapy), ionizing radiation, UV irradiation, oxidizing agents, and removal of modified bases by DNA glycosylases
  • APE is differentially expressed during development and in different tissues
  • This protein has diverse subcellular localization patterns which support the possibility of its interaction with numerous, other cellular proteins in addition to DNA repair within the nucleus
  • Regulation of APE by phosphorylation is mediated, at least in part, by casein kinase II
  • Increases in APE message and protein levels are observed upon the reintroduction of oxygen to hypoxic cells, and in some maligt tissue relative to normal tissue
  • Decreases in APE expression have been associated with the induction of cellular apoptosis.

Compare Similar Items

Show Difference

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Proteintech Group Inc

50-172-6212

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Antigen:
APEX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APEX1

Gene Alias:
AP endonuclease 1, APE, APE1, APE1,APEX1, APEN, APEX, APEX nuclease, APEX1, APX, HAP1, Protein REF 1, REF1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11792, 328, 79116

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P27695, P28352, P43138

Gene Symbols:
APEX1

Immunogen:
APEX1 Fusion Protein Ag0397

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Antigen:
MYL12B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYL12B

Gene Alias:
MLC 2, MLC 2A, MLC B, MLC20, MRLC2, MYL12B, MYLC2B, SHUJUN 1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
103910, 50685, 67938

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O14950, P18666, Q3THE2

Gene Symbols:
Myl12b

Immunogen:
MYL12B Fusion Protein Ag0398

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Antigen:
TRAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAP1

Gene Alias:
HSP 75, HSP75, HSP90L, TNFR associated protein 1, TRAP 1, TRAP1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10131, 287069, 68015

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q12931, Q5XHZ0, Q9CQN1

Gene Symbols:
Trap1

Immunogen:
TRAP1 Fusion Protein Ag0400

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Antigen:
TRIM32

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM32

Gene Alias:
72 kDa Tat interacting protein, BBS11, HT2A, LGMD2H, TATIP, TRIM32, tripartite motif containing 32, Zinc finger protein HT2A

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22954, 313264, 69807

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q13049, Q8CH72

Gene Symbols:
Trim32

Immunogen:
TRIM32 Fusion Protein Ag0401

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG