50-172-6425
IA-2/PTPRN Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6425-Each-of-1 | In Stock | ₹ 42,443.75 |
50-172-6425 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
IA-2/PTPRN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPRN
Gene Alias
IA 2, IA 2/PTP, IA2, ICA 512, ICA3, ICA512, Islet cell antigen 512, Islet cell autoantigen 3, PTP IA 2, PTPRN, R PTP N
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116660, 19275, 5798
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.19 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q16849, Q60673, Q63259
Gene Symbols
PTPRN
Immunogen
IA-2/PTPRN Fusion Protein Ag0923
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- IA-2 (insulinoma-associated protein 2, ICA512, PTPRN) is a member of the transmembrane protein tyrosine phosphatase (PTP) family located in secretory granules of neuroendocrine cells
- The IA-2 protein is 979 amino acids in length and consists of a luminal domain, transmembrane domain, and cytoplasmic domain
- Although a member of the PTP family, IA-2 lacks phosphatase activity with known substrates due to amino acid substitutions at critical sites in its PTP domain
- Two paralog RPTPs, IA-2 and IA-2beta were identified as major autoantigens in type-1 diabetes mellitus
- On granule exocytosis, the IA-2 cytoplasmic domain is cleaved and the resulting cytosolic fragment moves into the nucleus where it enhances the levels of phosphorylated STAT5 and STAT3, thereby inducing insulin gene transcription and granule biogenesis
- IA-2 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.
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Antigen: IA-2/PTPRN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPRN
Gene Alias: IA 2, IA 2/PTP, IA2, ICA 512, ICA3, ICA512, Islet cell antigen 512, Islet cell autoantigen 3, PTP IA 2, PTPRN, R PTP N
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116660, 19275, 5798
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.19 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q16849, Q60673, Q63259
Gene Symbols: PTPRN
Immunogen: IA-2/PTPRN Fusion Protein Ag0923
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IA-2/PTPRN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPRN
Gene Alias:
IA 2, IA 2/PTP, IA2, ICA 512, ICA3, ICA512, Islet cell antigen 512, Islet cell autoantigen 3, PTP IA 2, PTPRN, R PTP N
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116660, 19275, 5798
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.19 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q16849, Q60673, Q63259
Gene Symbols:
PTPRN
Immunogen:
IA-2/PTPRN Fusion Protein Ag0923
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: STMN2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STMN2
Gene Alias: Protein SCG10, SCG10, SCGN10, SGC10, Stathmin 2, stathmin like 2, STMN2
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11075, 20257, 84510
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.18 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P21818, P55821, Q93045
Gene Symbols: Stmn2
Immunogen: STMN2 Fusion Protein Ag0929
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
STMN2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STMN2
Gene Alias:
Protein SCG10, SCG10, SCGN10, SGC10, Stathmin 2, stathmin like 2, STMN2
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11075, 20257, 84510
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.18 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P21818, P55821, Q93045
Gene Symbols:
Stmn2
Immunogen:
STMN2 Fusion Protein Ag0929
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RBM15
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBM15
Gene Alias: One twenty two protein 1, OTT, OTT1, RBM15, RNA binding motif protein 15, SPEN
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 229700, 64783, 684233
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.32 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: Q0VBL3, Q96T37
Gene Symbols: RBM15
Immunogen: RBM15 Fusion Protein Ag0938
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RBM15
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RBM15
Gene Alias:
One twenty two protein 1, OTT, OTT1, RBM15, RNA binding motif protein 15, SPEN
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
229700, 64783, 684233
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.32 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q0VBL3, Q96T37
Gene Symbols:
RBM15
Immunogen:
RBM15 Fusion Protein Ag0938
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Cytokeratin 6A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KRT6A
Gene Alias: CK 6A, CK 6D, CK6A, CK6C, CK6D, Cytokeratin 6A, Cytokeratin 6D, Hom s 5, K6A, K6C, K6D, keratin 6A, KRT conserve, KRT6, KRT6A, KRT6C, KRT6D, Type II keratin Kb6
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16687, 3853, 683313
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.21 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P02538, P50446, Q4FZU2
Gene Symbols: Krt6a
Immunogen: Cytokeratin 6A Fusion Protein Ag0882
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cytokeratin 6A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRT6A
Gene Alias:
CK 6A, CK 6D, CK6A, CK6C, CK6D, Cytokeratin 6A, Cytokeratin 6D, Hom s 5, K6A, K6C, K6D, keratin 6A, KRT conserve, KRT6, KRT6A, KRT6C, KRT6D, Type II keratin Kb6
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16687, 3853, 683313
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.21 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P02538, P50446, Q4FZU2
Gene Symbols:
Krt6a
Immunogen:
Cytokeratin 6A Fusion Protein Ag0882
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG