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50-172-6432

APOBEC3C Rabbit anti-Human, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-172-6432-Each-of-1 In Stock ₹ 42,443.75

50-172-6432 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

APOBEC3C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APOBEC3C

Gene Alias

APOBEC1 like, APOBEC1L, APOBEC3, APOBEC3C, ARDC2, ARDC4, ARP5, bK150C2.3, PBI, Phorbolin I

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27350

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.17 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

Q9NRW3

Gene Symbols

APOBEC3C

Immunogen

APOBEC3C Fusion Protein Ag0886

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • APOBEC (apolipoprotein B mRNA editing enzyme, catalytic) proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
  • The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22
  • Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA
  • Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses
  • Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome
  • Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication
  • This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.

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Img

Proteintech Group Inc

50-172-6432

--

Antigen:
APOBEC3C
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APOBEC3C
Gene Alias:
APOBEC1 like, APOBEC1L, APOBEC3, APOBEC3C, ARDC2, ARDC4, ARP5, bK150C2.3, PBI, Phorbolin I
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27350
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.17 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q9NRW3
Gene Symbols:
APOBEC3C
Immunogen:
APOBEC3C Fusion Protein Ag0886
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Proteintech Group Inc

50-172-6433

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Antigen:
DLX5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DLX5
Gene Alias:
distal less homeobox 5, DLX5, Homeobox protein DLX 5
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13395, 1749, 25431
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P50575, P56178, P70396
Gene Symbols:
DLX5
Immunogen:
DLX5 Fusion Protein Ag0910
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

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Proteintech Group Inc

50-172-6434

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Antigen:
CD138/Syndecan-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SDC1
Gene Alias:
CD138, SDC, SDC1, SYND1, syndecan, syndecan 1
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20969, 25216, 6382
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P18827, P18828, P26260
Gene Symbols:
SDC1
Immunogen:
CD138/Syndecan-1 Fusion Protein Ag0823
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

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Proteintech Group Inc

50-172-6435

--

Antigen:
PEX14
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PEX14
Gene Alias:
NAPP2, Peroxin 14, PEX14, Pex14p, PTS1 receptor docking protein
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5195, 56273, 64460
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration:
0.33 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
O75381, Q642G4, Q9R0A0
Gene Symbols:
PEX14
Immunogen:
PEX14 Fusion Protein Ag0932
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG