50-172-6660
Histone H2A.X Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6660-Each-of-1 | In Stock | ₹ 42,443.75 |
50-172-6660 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AFX
Gene Alias
H2A histone family, member X, H2A.X, H2A/X, H2AFX, H2AX, Histone H2A.x
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014, 500987
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.3 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
P16104, P27661
Gene Symbols
H2afx
Immunogen
Histone H2A.X Fusion Protein Ag1305
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Histone H2A
- X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A
- x contains 143 amino acid residues
- Histone H2A
- X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A
- X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A
- X maps to the 11q23
- 2-q23
- 3 region of the human chromosome
- Histone H2A
- x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A
- x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
Compare Similar Items
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Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AFX
Gene Alias: H2A histone family, member X, H2A.X, H2A/X, H2AFX, H2AX, Histone H2A.x
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014, 500987
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P16104, P27661
Gene Symbols: H2afx
Immunogen: Histone H2A.X Fusion Protein Ag1305
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AFX
Gene Alias:
H2A histone family, member X, H2A.X, H2A/X, H2AFX, H2AX, Histone H2A.x
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014, 500987
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2afx
Immunogen:
Histone H2A.X Fusion Protein Ag1305
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MECP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MECP2
Gene Alias: AUTSX3, MeCp 2 protein, MECP2, Methyl CpG binding protein 2, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTS, RTT
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17257, 29386, 4204
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration: 0.18 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P51608, Q00566, Q9Z2D6
Gene Symbols: Mecp2
Immunogen: MECP2 Fusion Protein Ag1309
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MECP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MECP2
Gene Alias:
AUTSX3, MeCp 2 protein, MECP2, Methyl CpG binding protein 2, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTS, RTT
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17257, 29386, 4204
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration:
0.18 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P51608, Q00566, Q9Z2D6
Gene Symbols:
Mecp2
Immunogen:
MECP2 Fusion Protein Ag1309
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LYPLA3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PLA2G15
Gene Alias: 1 O acylceramide synthase, ACS, Group XV phospholipase A2, GXVPLA2, LCAT like lysophospholipase, LLPL, LPLA2, LYPLA3, Lysophospholipase 3, Lysosomal phospholipase A2, phospholipase A2, group XV, PLA2G15
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 192654, 23659, 361401
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 0.13 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: Q675A5, Q8NCC3, Q8VEB4
Gene Symbols: Pla2g15
Immunogen: LYPLA3 Fusion Protein Ag1304
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LYPLA3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PLA2G15
Gene Alias:
1 O acylceramide synthase, ACS, Group XV phospholipase A2, GXVPLA2, LCAT like lysophospholipase, LLPL, LPLA2, LYPLA3, Lysophospholipase 3, Lysosomal phospholipase A2, phospholipase A2, group XV, PLA2G15
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
192654, 23659, 361401
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.13 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q675A5, Q8NCC3, Q8VEB4
Gene Symbols:
Pla2g15
Immunogen:
LYPLA3 Fusion Protein Ag1304
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ATP1A3 (C-terminal)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATP1A3
Gene Alias: ATP1A3, DYT12, RDP, Sodium pump subunit alpha 3
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 232975, 24213, 478
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.33 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P06687, P13637, Q6PIC6
Gene Symbols: ATP1A3
Immunogen: ATP1A3 (C-terminal) Fusion Protein Ag1313
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ATP1A3 (C-terminal)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATP1A3
Gene Alias:
ATP1A3, DYT12, RDP, Sodium pump subunit alpha 3
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
232975, 24213, 478
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.33 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P06687, P13637, Q6PIC6
Gene Symbols:
ATP1A3
Immunogen:
ATP1A3 (C-terminal) Fusion Protein Ag1313
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG