50-172-7218

BubR1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-172-7218-Each-of-1 In Stock ₹ 44,150.23

50-172-7218 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

BubR1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BUB1B

Gene Alias

Bub1A, BUB1B, BUB1beta, BubR1, hBUBR1, MAD3L, Protein SSK1, SSK1

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12236, 701

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

O60566, Q9Z1S0

Gene Symbols

BUB1B

Immunogen

BubR1 Fusion Protein Ag2053

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • BUBR1 is a member of the Ser/Thr protein kinase family
  • It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle
  • Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to maligt transformations
  • Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
  • They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
  • hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
  • BUBR1 has been detected in human cancers
  • It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.

Compare Similar Items

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Proteintech Group Inc

50-172-7218

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Antigen:
BubR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BUB1B

Gene Alias:
Bub1A, BUB1B, BUB1beta, BubR1, hBUBR1, MAD3L, Protein SSK1, SSK1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12236, 701

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O60566, Q9Z1S0

Gene Symbols:
BUB1B

Immunogen:
BubR1 Fusion Protein Ag2053

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7220

--


Antigen:
SNX4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SNX4

Gene Alias:
SNX4, sorting nexin 4

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
360725, 69150, 8723

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O95219, Q91YJ2

Gene Symbols:
Snx4

Immunogen:
SNX4 Fusion Protein Ag2058

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7221

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Antigen:
FNTB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FNTB

Gene Alias:
FNTB, FPTB, FTase beta

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110606, 2342, 64511

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P49356, Q02293, Q8K2I1

Gene Symbols:
Fntb

Immunogen:
FNTB Fusion Protein Ag2061

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7222

--


Antigen:
PTP4A1/PRL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTP4A1

Gene Alias:
HH72, PRL 1, PRL1, PTP(CAAX1), PTP(CAAXI), PTP4A1, PTPCAAX1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19243, 29463, 7803

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q63739, Q78EG7, Q93096

Gene Symbols:
PTP4A1

Immunogen:
PTP4A1/PRL1 Fusion Protein Ag2067

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG