50-172-7863

Clusterin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-172-7863-Each-of-1 In Stock ₹ 42,443.75

50-172-7863 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

Clusterin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CLU

Gene Alias

AAG4, Apo J, APOJ, ApoJalpha, ApoJbeta, Apolipoprotein J, CLI, CLU, clusterin, Complement cytolysis inhibitor, Ku70 binding protein 1, KUB1, NA1/NA2, SGP 2, SGP2, SP 40, TRPM 2, TRPM2

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1191, 12759, 24854

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P05371, P10909, Q06890

Gene Symbols

CLU

Immunogen

Clusterin Fusion Protein Ag2889

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Proteintech Group Inc

50-172-6534

--

Img

Proteintech Group Inc

50-172-9963

--

Img

Proteintech Group Inc

50-173-0811

--

Img

Proteintech Group Inc

50-172-6386

--

Img

Proteintech Group Inc

50-172-6380

--

Img

Proteintech Group Inc

50-172-6755

--

Img

Proteintech Group Inc

50-172-7470

--

Img

Proteintech Group Inc

50-173-4254

--

Description

  • Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
  • Prevents stress-induced aggregation of blood plasma proteins
  • Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro)
  • Does not require ATP
  • Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70
  • Does not refold proteins by itself
  • Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation
  • Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement
  • Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins
  • Promotes proteasomal degradation of COMMD1 and IKBKB
  • Modulates NF-kappa-B transcriptional activity
  • Nuclear isoforms promote apoptosis
  • Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis
  • Plays a role in the regulation of cell proliferation.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-172-7863

--


Antigen:
Clusterin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLU

Gene Alias:
AAG4, Apo J, APOJ, ApoJalpha, ApoJbeta, Apolipoprotein J, CLI, CLU, clusterin, Complement cytolysis inhibitor, Ku70 binding protein 1, KUB1, NA1/NA2, SGP 2, SGP2, SP 40, TRPM 2, TRPM2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1191, 12759, 24854

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P05371, P10909, Q06890

Gene Symbols:
CLU

Immunogen:
Clusterin Fusion Protein Ag2889

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7864

--


Antigen:
RHOF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RHOF

Gene Alias:
ARHF, Rho family GTPase Rif, Rho in filopodia, RHOF, RIF

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23912, 54509, 690130

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8BYP3, Q9HBH0

Gene Symbols:
RHOF

Immunogen:
RHOF Fusion Protein Ag2943

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7865

--


Antigen:
ALKBH3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALKBH3

Gene Alias:
ABH3, ALKBH3, DEPC 1, DEPC1, PCA1, Prostate cancer antigen 1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
221120, 69113

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q8K1E6, Q96Q83

Gene Symbols:
Alkbh3

Immunogen:
ALKBH3 Fusion Protein Ag2982

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7867

--


Antigen:
GATAD2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GATAD2A

Gene Alias:
GATAD2A, Hp66alpha, p66 alpha

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
234366, 290669, 54815

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q86YP4, Q8CHY6

Gene Symbols:
Gatad2a

Immunogen:
GATAD2A Fusion Protein Ag2947

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG