50-172-7873
ITGB1BP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-7873-Each-of-1 | In Stock | ₹ 42,443.75 |
50-172-7873 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
ITGB1BP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ITGB1BP1
Gene Alias
ICAP 1, ICAP 1A, ICAP 1alpha, ICAP 1B, ICAP1, ICAP1A, ICAP1B, ITGB1BP1
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16413, 298914, 9270
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.33 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O14713, O35671
Gene Symbols
ITGB1BP1
Immunogen
ITGB1BP1 Fusion Protein Ag2945
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1
- Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis
- Stimulates cellular proliferation in a fibronectin-dependent manner
- Involved in the regulation of beta-1 integrin-containing focal adhesion (FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with talin TLN1, and hence stimulates osteoblast spreading and migration in a fibronectin-and/or collagen-dependent manner
- Acts as a guanine nucleotide dissociation inhibitor (GDI) by regulating Rho family GTPases during integrin-mediated cell matrix adhesion; reduces the level of active GTP-bound form of both CDC42 and RAC1 GTPases upon cell adhesion to fibronectin
- Stimulates the release of active CDC42 from the membranes to maintain it in an inactive cytoplasmic pool
- Participates in the translocation of the Rho-associated protein kinase ROCK1 to membrane ruffles at cell leading edges of the cell membrane, leading to an increase of myoblast cell migration on laminin
- Plays a role in bone mineralization at a late stage of osteoblast differentiation; modulates the dynamic formation of focal adhesions into fibrillar adhesions, which are adhesive structures responsible for fibronectin deposition and fibrillogenesis
- Plays a role in blood vessel development; acts as a negative regulator of angiogenesis by attenuating endothelial cell proliferation and migration, lumen formation and sprouting angiogenesis by promoting AKT phosphorylation and inhibiting ERK1/2 phosphorylation through activation of the Notch signaling pathway
- Promotes transcriptional activity of the MYC promoter.
Compare Similar Items
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Antigen: ITGB1BP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ITGB1BP1
Gene Alias: ICAP 1, ICAP 1A, ICAP 1alpha, ICAP 1B, ICAP1, ICAP1A, ICAP1B, ITGB1BP1
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16413, 298914, 9270
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.33 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O14713, O35671
Gene Symbols: ITGB1BP1
Immunogen: ITGB1BP1 Fusion Protein Ag2945
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ITGB1BP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ITGB1BP1
Gene Alias:
ICAP 1, ICAP 1A, ICAP 1alpha, ICAP 1B, ICAP1, ICAP1A, ICAP1B, ITGB1BP1
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16413, 298914, 9270
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.33 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O14713, O35671
Gene Symbols:
ITGB1BP1
Immunogen:
ITGB1BP1 Fusion Protein Ag2945
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ACYP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACYP2
Gene Alias: Acylphosphatase 2, acylphosphatase 2, muscle type, ACYM, ACYP, ACYP2
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 364224, 75572, 98
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.13 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P14621, P35745, P56375
Gene Symbols: Acyp2
Immunogen: ACYP2 Fusion Protein Ag2948
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ACYP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACYP2
Gene Alias:
Acylphosphatase 2, acylphosphatase 2, muscle type, ACYM, ACYP, ACYP2
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
364224, 75572, 98
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.13 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P14621, P35745, P56375
Gene Symbols:
Acyp2
Immunogen:
ACYP2 Fusion Protein Ag2948
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TBCA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBCA
Gene Alias: CFA, TBCA, TCP1 chaperonin cofactor A, tubulin folding cofactor A, Tubulin specific chaperone A
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21371, 366995, 6902
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.27 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: O75347, P48428, Q6PEC1
Gene Symbols: Tbca
Immunogen: TBCA Fusion Protein Ag2950
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TBCA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBCA
Gene Alias:
CFA, TBCA, TCP1 chaperonin cofactor A, tubulin folding cofactor A, Tubulin specific chaperone A
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21371, 366995, 6902
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.27 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
O75347, P48428, Q6PEC1
Gene Symbols:
Tbca
Immunogen:
TBCA Fusion Protein Ag2950
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZFP36L1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZFP36L1
Gene Alias: Berg36, BRF1, Butyrate response factor 1, cMG1, EGF response factor 1, ERF 1, ERF1, Protein TIS11B, RNF162B, TIS11B, ZFP36L1
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12192, 29344, 677
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.25 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P17431, P23950, Q07352
Gene Symbols: ZFP36L1
Immunogen: ZFP36L1 Fusion Protein Ag2952
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ZFP36L1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZFP36L1
Gene Alias:
Berg36, BRF1, Butyrate response factor 1, cMG1, EGF response factor 1, ERF 1, ERF1, Protein TIS11B, RNF162B, TIS11B, ZFP36L1
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12192, 29344, 677
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P17431, P23950, Q07352
Gene Symbols:
ZFP36L1
Immunogen:
ZFP36L1 Fusion Protein Ag2952
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG