50-172-8008

LCK Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-172-8008-Each-of-1 In Stock ₹ 42,443.75

50-172-8008 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

LCK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LCK

Gene Alias

LCK, LSK, p56 LCK, p56lck, pp58lck, Protein YT16, Proto oncogene Lck, Tyrosine protein kinase Lck, YT16

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16818, 313050, 3932

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.17 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P06239, P06240, Q01621

Gene Symbols

Lck

Immunogen

LCK Fusion Protein Ag3176

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • LCK is a member of the Src-family tyrosine kinase, which are essential for signaling through the T-cell receptor (TCR) complex
  • Upon TCR triggering, LCK phosphorylates the ITAM motives in its zeta subunits establishing binding sites for the SH2 domains of the tyrosine kinase ZAP70, which is also phosphorylated by LCK and activated to generate subsequent signaling platforms by phosphorylation of adaptor LAT
  • The majority of LCK is localized to the plasma membrane, however, there is also a significant fraction associated with the Golgi apparatus which may contribute to Raf activation under conditions of weak stimulation through the TCR
  • LCK contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively
  • LCK is also involved in the regulation of apoptosis induced by various stimuli, but not by the death receptors
  • Diseases associated with LCK include Immunodeficiency 22 and CD45 deficiency
  • Alternatively splice variants of the LCK gene encoding different isoforms of the protein have been found.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-172-8008

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Antigen:
LCK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LCK

Gene Alias:
LCK, LSK, p56 LCK, p56lck, pp58lck, Protein YT16, Proto oncogene Lck, Tyrosine protein kinase Lck, YT16

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16818, 313050, 3932

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P06239, P06240, Q01621

Gene Symbols:
Lck

Immunogen:
LCK Fusion Protein Ag3176

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8009

--


Antigen:
PREPL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PREPL

Gene Alias:
KIAA0436, PPCEL, PREPL, prolyl endopeptidase like, Prolylendopeptidase like

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
213760, 298771, 9581

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.19 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q4J6C6, Q5HZA6, Q8C167

Gene Symbols:
PREPL

Immunogen:
PREPL Fusion Protein Ag3196

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8010

--


Antigen:
TPP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TPP1

Gene Alias:
CLN2, GIG1, LPIC, TPP 1, TPP I, TPP1, Tripeptidyl aminopeptidase, Tripeptidyl peptidase 1, tripeptidyl peptidase I, UNQ267/PRO304

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1200, 12751, 83534

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O14773, O89023, Q9EQV6

Gene Symbols:
Tpp1

Immunogen:
TPP1 Fusion Protein Ag3173

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8011

--


Antigen:
Ephrin A3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EFNA3

Gene Alias:
EFL 2, EFL2, EFNA3, Ehk1 L, EHK1 ligand, ephrin A3, EPLG3, LERK 3, LERK3

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13638, 170901, 1944

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O08545, P52797

Gene Symbols:
Efna3

Immunogen:
Ephrin A3 Fusion Protein Ag3188

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG