50-172-8366
GCAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-8366-Each-of-1 | In Stock | ₹ 42,443.75 |
50-172-8366 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
GCAP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GUCA1A
Gene Alias
C6orf131, COD3, GCAP, GCAP 1, GCAP1, Guanylate cyclase activator 1A, GUCA, GUCA1, GUCA1A
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14913, 2978, 301233
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
0.45 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P43080, P43081
Gene Symbols
Guca1a
Immunogen
GCAP1 Fusion Protein Ag4017
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Guanylate cyclase-activating protein is a l Ca(2+)-binding protein that upregulates synthesis of cGMP in photoreceptors
- The known mammalian GCAPs are more than 90% similar, consisting of 201 to 205 amino acids, and containing 3 identically conserved Ca(2+)-binding sites
- The GUCA1A gene, also termed GCAP1, is transcribed into a single 1.7-kb mRNA species detectable only in the retina
- In a 4-generation British family with typical clinical features of autosomal domit cone dystrophy a tyr99-to-cys mutation) in the GUCA1A gene has been identified
- Another family with a pro50-to-leu mutation in GUCA1A demonstrated phenotypic variability ranging from mild photophobia to rod-cone dystrophy
- The mutant protein could activate guanylate cyclase 1 (GUCY2D) and displayed similar calcium sensitivity to wildtype protein
- However, there was a marked increase in the susceptibility to protease degradation and a reduction in the thermal stability of the pro50-to-leu mutation, which may depress cellular concentration and thereby contribute to retinal cell mortality.
Compare Similar Items
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Antigen: GCAP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GUCA1A
Gene Alias: C6orf131, COD3, GCAP, GCAP 1, GCAP1, Guanylate cyclase activator 1A, GUCA, GUCA1, GUCA1A
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14913, 2978, 301233
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 0.45 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P43080, P43081
Gene Symbols: Guca1a
Immunogen: GCAP1 Fusion Protein Ag4017
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GCAP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GUCA1A
Gene Alias:
C6orf131, COD3, GCAP, GCAP 1, GCAP1, Guanylate cyclase activator 1A, GUCA, GUCA1, GUCA1A
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14913, 2978, 301233
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.45 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P43080, P43081
Gene Symbols:
Guca1a
Immunogen:
GCAP1 Fusion Protein Ag4017
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GAGE7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GAGE7
Gene Alias: AL4, Cancer/testis antigen 4.7, CT4.7, G antigen 7, GAGE 12I, GAGE 7, GAGE 7B, GAGE 8, GAGE family, GAGE12I, GAGE7, GAGE7B
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2579
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.35 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: O76087
Gene Symbols: GAGE7
Immunogen: GAGE7 Fusion Protein Ag4018
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GAGE7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GAGE7
Gene Alias:
AL4, Cancer/testis antigen 4.7, CT4.7, G antigen 7, GAGE 12I, GAGE 7, GAGE 7B, GAGE 8, GAGE family, GAGE12I, GAGE7, GAGE7B
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2579
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.35 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
O76087
Gene Symbols:
GAGE7
Immunogen:
GAGE7 Fusion Protein Ag4018
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: VRK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VRK2
Gene Alias: vaccinia related kinase 2, VRK2
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 360991, 69922, 7444
Content And Storage: -20°C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.19 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: Q86Y07, Q8BN21
Gene Symbols: Vrk2
Immunogen: VRK2 Fusion Protein Ag4019
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VRK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VRK2
Gene Alias:
vaccinia related kinase 2, VRK2
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
360991, 69922, 7444
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.19 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q86Y07, Q8BN21
Gene Symbols:
Vrk2
Immunogen:
VRK2 Fusion Protein Ag4019
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PDK4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDK4
Gene Alias: PDK4
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27273, 5166, 89813
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.19 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: O54937, O70571, Q16654
Gene Symbols: Pdk4
Immunogen: PDK4 Fusion Protein Ag3629
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PDK4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDK4
Gene Alias:
PDK4
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27273, 5166, 89813
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.19 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
O54937, O70571, Q16654
Gene Symbols:
Pdk4
Immunogen:
PDK4 Fusion Protein Ag3629
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG