50-172-8412

CUGBP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-172-8412-Each-of-1 In Stock ₹ 42,443.75

50-172-8412 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

CUGBP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CELF1

Gene Alias

Bruno like protein 2, BRUNOL2, CELF 1, CELF1, CUG BP, CUG BP1, CUGBP, CUGBP1, Deadenylation factor CUG BP, EDEN BP homolog, hNab50, NAB50, RNA binding protein BRUNOL 2

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10658, 13046, 362160

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.37 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P28659, Q4QQT3, Q92879

Gene Symbols

Celf1

Immunogen

CUGBP1 Fusion Protein Ag3677

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Myotonic dystrophy (MD) is an autosomal domit neuromuscular disease that is associated with a (CTG)n repeat expansion in the 3′-untranslated region of the myotonin protein kinase (Mt-PK) gene
  • A (CUG) n oligonucleotides triplet repeat pre-mRNA/mRNA binding protein may play an important role in DM pathogenesis
  • HeLa cell protein, CUG-BP1, has been purified based upon its ability to bind specifically to (CUG) 8 oligonucleotides in vitro
  • CUG-BP1 is the major (CUG) 8 binding activity in normal cells
  • CUG-BP1 has been identified as isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50
  • The CUG-BP/hNab50 protein is localized predomitly in the nucleus and is associated with polyadenylated RNAs in vivo
  • In vitro RNA-binding/photocrosslinking studies demonstrate that CUG-BP/hNab50 binds to RNAs containing the Mt-PK 3-UTR
  • The (CUG) n repeat region in Mt-PK mRNA is a binding site for CUG-BP/hNab50 in vivo, and triplet repeat expansion leads to sequestration of this hnRNP on mutant Mt-PK transcripts.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-172-8412

--


Antigen:
CUGBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CELF1

Gene Alias:
Bruno like protein 2, BRUNOL2, CELF 1, CELF1, CUG BP, CUG BP1, CUGBP, CUGBP1, Deadenylation factor CUG BP, EDEN BP homolog, hNab50, NAB50, RNA binding protein BRUNOL 2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10658, 13046, 362160

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P28659, Q4QQT3, Q92879

Gene Symbols:
Celf1

Immunogen:
CUGBP1 Fusion Protein Ag3677

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8414

--


Antigen:
FAIM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FAIM

Gene Alias:
FAIM, FAIM1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140930, 23873, 55179

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q8R5H8, Q9NVQ4, Q9WUD8

Gene Symbols:
FAIM

Immunogen:
FAIM Fusion Protein Ag3685

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8419

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Antigen:
NKX2-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NKX2-2

Gene Alias:
Homeobox protein Nkx 2.2, NK2 homeobox 2, NKX2 2, NKX2.2, NKX2-2, NKX2B

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18088, 366214, 4821

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
0.49 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O95096, P42586

Gene Symbols:
Nkx2-2

Immunogen:
NKX2-2 Fusion Protein Ag4069

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8421

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Antigen:
DBNL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DBNL

Gene Alias:
ABP1, Cervical SH3P7, CMAP, DBNL, Drebrin F, drebrin like, Drebrin like protein, HIP 55, SH3P7

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13169, 28988, 83527

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.66 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q62418, Q9JHL4, Q9UJU6

Gene Symbols:
DBNL

Immunogen:
DBNL Fusion Protein Ag4078

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG