50-172-8474

IL-17 Rabbit anti-Human, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-172-8474-Each-of-1 In Stock ₹ 42,443.75

50-172-8474 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

IL-17

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL17A

Gene Alias

CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A, interleukin 17A

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3605

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.34 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q16552

Gene Symbols

IL17A

Immunogen

IL-17 Fusion Protein Ag3733

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody got 32-35 kDa band in western blot, maybe due to homodimer formation and differential glycosylations
  • Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

Compare Similar Items

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Proteintech Group Inc

50-172-8474

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Antigen:
IL-17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL17A

Gene Alias:
CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A, interleukin 17A

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3605

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.34 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q16552

Gene Symbols:
IL17A

Immunogen:
IL-17 Fusion Protein Ag3733

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8477

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Antigen:
CTNS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNS

Gene Alias:
CTNS, CTNS LSB, Cystinosin, cystinosis, nephropathic, PQLC4

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1497, 287478, 83429

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O60931, P57757

Gene Symbols:
Ctns

Immunogen:
CTNS Fusion Protein Ag3904

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8478

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Antigen:
FREM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FREM1

Gene Alias:
C9orf143, C9orf145, C9orf154, FREM1, Protein QBRICK, QBRICK, RP11 439N12.3

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
158326

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q5H8C1

Gene Symbols:
FREM1

Immunogen:
FREM1 Fusion Protein Ag3617

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Proteintech Group Inc

50-172-8479

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Antigen:
RHOXF2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RHOXF2

Gene Alias:
PEPP 2, PEPP2, Rhox homeobox family member 2, Rhox homeobox family, member 2, RHOXF2, Testis homeobox gene 1, THG1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84528

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q9BQY4

Gene Symbols:
RHOXF2

Immunogen:
RHOXF2 Fusion Protein Ag3602

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG