50-172-8708

CD86 Rabbit anti-Human, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-172-8708-Each-of-1 In Stock ₹ 42,443.75

50-172-8708 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

CD86

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD86

Gene Alias

Activation B7 2 antigen, B7 2, B70, BU63, CD28LG2, CD86, CD86 molecule, FUN 1, LAB72

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

942

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Western Blot

Concentration

0.19 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P42081

Gene Symbols

CD86

Immunogen

CD86 Fusion Protein Ag4063

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody detects a band of approximately 70 kDa, consistent with glycosylated form of CD86
  • CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

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Img

Proteintech Group Inc

50-172-8708

--


Antigen:
CD86

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD86

Gene Alias:
Activation B7 2 antigen, B7 2, B70, BU63, CD28LG2, CD86, CD86 molecule, FUN 1, LAB72

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
942

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.19 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P42081

Gene Symbols:
CD86

Immunogen:
CD86 Fusion Protein Ag4063

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Proteintech Group Inc

50-172-8709

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Antigen:
B4GALNT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
B4GALNT1

Gene Alias:
B4GALNT1, GALGT, GalNAc T, GALNACT, GM2/GD2 synthase, SIAT2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2583

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q00973

Gene Symbols:
B4GALNT1

Immunogen:
B4GALNT1 Fusion Protein Ag4065

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8716

--


Antigen:
KIF22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIF22

Gene Alias:
KID, KIF22, kinesin family member 22, Kinesin like protein 4, Kinesin like protein KIF22, KNSL4, OBP, OBP 1, OBP 2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110033, 293502, 3835

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.39 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q14807, Q3V300, Q5I0E8

Gene Symbols:
KIF22

Immunogen:
KIF22 Fusion Protein Ag4254

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-8718

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Antigen:
TRIM38

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM38

Gene Alias:
RING finger protein 15, RNF15, RORET, TRIM38, tripartite motif containing 38, Zinc finger protein RoRet

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10475

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O00635

Gene Symbols:
TRIM38

Immunogen:
TRIM38 Fusion Protein Ag3840

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG