50-172-9118
Chk2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-9118-Each-of-1 | In Stock | ₹ 42,443.75 |
50-172-9118 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
Chk2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CHEK2
Gene Alias
CDS1, CHEK2, Chk2, HuCds1, LFS2, PP1425, RAD53
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11200, 114212, 50883
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Concentration
0.23 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O96017, Q9Z265
Gene Symbols
Chek2
Immunogen
Chk2 Fusion Protein Ag5065
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Chk2 (checkpoint kinase 2) is the mammalian homolog of the Saccharomyces cerevisiae Rad53 and is required for the DNA damage and replication checkpoints
- In response to low-dose ionizing radiation (IR), which occurs in an ataxia telangiectasia mutated (ATM)-dependent manner, Chk2 can phosphorylate the mitosis-inducing phosphatase Cdc25C on an inhibitory site, blocking entry into mitosis, and p53 on a regulatory site, causing G1 arrest
- In human tissues, Chk2 is homogeneously expressed in renewing cell populations such as epidermis or intestine, heterogeneous in conditionally renewing tissues, and absent or at low level in static tissues such as muscle or brain
- Mutations in Chk2 inactivates DNA damage checkpoint pathway involving Chk2 in lung cancer suggesting that reduced expression of Chk2 may be responsible for the development of lung cancer
- The Chk2-/- knockout cells are resistant to DNA damage-induced apoptosis, defective for p53 stabilization and for induction of p53-dependent transcripts such as p21 in response to gamma irradiation.
Compare Similar Items
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Antigen: Chk2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CHEK2
Gene Alias: CDS1, CHEK2, Chk2, HuCds1, LFS2, PP1425, RAD53
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11200, 114212, 50883
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Concentration: 0.23 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O96017, Q9Z265
Gene Symbols: Chek2
Immunogen: Chk2 Fusion Protein Ag5065
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Chk2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CHEK2
Gene Alias:
CDS1, CHEK2, Chk2, HuCds1, LFS2, PP1425, RAD53
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11200, 114212, 50883
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Concentration:
0.23 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O96017, Q9Z265
Gene Symbols:
Chek2
Immunogen:
Chk2 Fusion Protein Ag5065
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PDE8A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDE8A
Gene Alias: HsT19550, PDE8A, phosphodiesterase 8A
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18584, 308776, 5151
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.42 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O60658, O88502
Gene Symbols: Pde8a
Immunogen: PDE8A Fusion Protein Ag5069
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PDE8A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDE8A
Gene Alias:
HsT19550, PDE8A, phosphodiesterase 8A
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18584, 308776, 5151
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.42 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O60658, O88502
Gene Symbols:
Pde8a
Immunogen:
PDE8A Fusion Protein Ag5069
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD43
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SPN
Gene Alias: CD43, Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, LSN, sialophorin, SPN
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6693
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.39 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P16150
Gene Symbols: SPN
Immunogen: CD43 Fusion Protein Ag4836
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CD43
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SPN
Gene Alias:
CD43, Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, LSN, sialophorin, SPN
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6693
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.39 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P16150
Gene Symbols:
SPN
Immunogen:
CD43 Fusion Protein Ag4836
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PPFIBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPFIBP1
Gene Alias: hSGT2, hSgt2p, KIAA1230, L2, Liprin beta 1, PPFIBP1
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 312855, 67533, 8496
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration: 0.18 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q86W92, Q8C8U0
Gene Symbols: Ppfibp1
Immunogen: PPFIBP1 Fusion Protein Ag4884
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PPFIBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPFIBP1
Gene Alias:
hSGT2, hSgt2p, KIAA1230, L2, Liprin beta 1, PPFIBP1
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
312855, 67533, 8496
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration:
0.18 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q86W92, Q8C8U0
Gene Symbols:
Ppfibp1
Immunogen:
PPFIBP1 Fusion Protein Ag4884
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG