50-172-9224
MARCH8 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-9224-Each-of-1 | In Stock | ₹ 42,443.75 |
50-172-9224 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
MARCH8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MARCH8
Gene Alias
c MIR, MARCH VIII, MARCH8, MIR, RING finger protein 178, RNF178
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
220972, 71779
Content And Storage
-20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
0.13 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q5T0T0, Q9DBD2
Gene Symbols
MARCH8
Immunogen
MARCH8 Fusion Protein Ag5268
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- MARCH8 (c-MIR) is a novel E3 ubiquitin ligase designated as the modulator of immune recognition (MIR) family, whose catalytic domain is a variant RING domain (RING-CH domain)
- MARCH8 was found as a functional and structural homolog of KSHV MIR1 and MIR2
- MARCH8 targets B7-2 to lysosomal degradation and down-regulates the B7-2 surface expression through ubiquitination of its cytoplasmic tail
- Furthermore, MARCH8 has been shown to down-regulate the expression of transferrin receptor and Fas, an important molecule for the induction of apoptosis
- MARCH8 is the first example of an E3 ubiquitin ligase that is capable of inhibiting MHC II expression
- Recent findings suggest that MARCH8 may regulate immune responses by promoting ubiquitination of MHC-II and CD86, leading to their subsequent endocytosis and lysosomal degradation.
Compare Similar Items
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Antigen: MARCH8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MARCH8
Gene Alias: c MIR, MARCH VIII, MARCH8, MIR, RING finger protein 178, RNF178
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 220972, 71779
Content And Storage: -20°C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.13 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q5T0T0, Q9DBD2
Gene Symbols: MARCH8
Immunogen: MARCH8 Fusion Protein Ag5268
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MARCH8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MARCH8
Gene Alias:
c MIR, MARCH VIII, MARCH8, MIR, RING finger protein 178, RNF178
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
220972, 71779
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.13 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q5T0T0, Q9DBD2
Gene Symbols:
MARCH8
Immunogen:
MARCH8 Fusion Protein Ag5268
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MARCKSL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MARCKSL1
Gene Alias: F52, Mac MARCKS, MACMARCKS, MARCKS like 1, MARCKS like protein 1, MARCKS related protein, MARCKSL1, MLP, MLP1, MRP
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 65108
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 0.36 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P49006
Gene Symbols: MARCKSL1
Immunogen: MARCKSL1 Fusion Protein Ag5274
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MARCKSL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MARCKSL1
Gene Alias:
F52, Mac MARCKS, MACMARCKS, MARCKS like 1, MARCKS like protein 1, MARCKS related protein, MARCKSL1, MLP, MLP1, MRP
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
65108
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.36 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P49006
Gene Symbols:
MARCKSL1
Immunogen:
MARCKSL1 Fusion Protein Ag5274
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CDC26
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDC26
Gene Alias: ANAPC12, APC12, C9orf17, CDC26
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 246184, 366381, 66440
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.58 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: Q6YDN7, Q8NHZ8, Q99JP4
Gene Symbols: Cdc26
Immunogen: CDC26 Fusion Protein Ag5276
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CDC26
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDC26
Gene Alias:
ANAPC12, APC12, C9orf17, CDC26
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
246184, 366381, 66440
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.58 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q6YDN7, Q8NHZ8, Q99JP4
Gene Symbols:
Cdc26
Immunogen:
CDC26 Fusion Protein Ag5276
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PRDM5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRDM5
Gene Alias: PFM2, PR domain containing 5, PR domain containing protein 5, PRDM5
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11107, 689788, 70779
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.35 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: Q9CXE0, Q9NQX1
Gene Symbols: Prdm5
Immunogen: PRDM5 Fusion Protein Ag5277
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PRDM5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRDM5
Gene Alias:
PFM2, PR domain containing 5, PR domain containing protein 5, PRDM5
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11107, 689788, 70779
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.35 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q9CXE0, Q9NQX1
Gene Symbols:
Prdm5
Immunogen:
PRDM5 Fusion Protein Ag5277
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG