50-172-9306

Myocilin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-172-9306-Each-of-1 In Stock ₹ 42,443.75

50-172-9306 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

Myocilin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYOC

Gene Alias

GLC1A, GPOA, JOAG, JOAG1, MYOC, Myocilin, TIGR

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17926, 4653, 81523

Content And Storage

-20°C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

0.33 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O70624, Q99972, Q9R1J4

Gene Symbols

Myoc

Immunogen

Myocilin Fusion Protein Ag5492

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Myocilin is an extracellular protein expressed in the eye, including the retina, trabecular meshwork and ciliary body
  • Myocilin can form homomultimers in vivo and can also associate with components of the ECM via interactions with the Hep II domain of FibroPVRL1
  • In addition, myocilin interacts with myosin regulatory light chain, a component of the myosin motor protein complex
  • This interaction implies a role for myocilin in the actomyosin system, linking myocilin to the functional status of the trabecular meshwork (TM), which is responsible for controlling the intraocular pressure (IOP)
  • Alterations in functions of the TM may lead to IOP elevation and development of glaucoma, a major cause of blindness
  • Myocilin is encoded by MYOC (also designated TIGR), a gene that maps to the GLC1A locus on chromosome 1q24.3 and is susceptible to mutations
  • Mutations in the MYOC gene are specifically linked with primary open angle glaucoma (POAG), a blinding disease characterized by progressive loss of retinal ganglion cells.

Compare Similar Items

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Img

Proteintech Group Inc

50-172-9306

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Antigen:
Myocilin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYOC

Gene Alias:
GLC1A, GPOA, JOAG, JOAG1, MYOC, Myocilin, TIGR

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17926, 4653, 81523

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O70624, Q99972, Q9R1J4

Gene Symbols:
Myoc

Immunogen:
Myocilin Fusion Protein Ag5492

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-9309

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Antigen:
GCLM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GCLM

Gene Alias:
Gamma ECS regulatory subunit, GCLM, GCS light chain, GLCLR

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14630, 2730, 29739

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration:
0.21 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O09172, P48507, P48508

Gene Symbols:
GCLM

Immunogen:
GCLM Fusion Protein Ag5497

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-9310

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Antigen:
PIAS4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIAS4

Gene Alias:
E3 SUMO protein ligase PIAS4, PIAS gamma, PIAS4, Piasg, PIASY, ZMIZ6

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
362827, 51588, 59004

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8N2W9, Q9JM05

Gene Symbols:
Pias4

Immunogen:
PIAS4 Fusion Protein Ag5498

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-9314

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Antigen:
NR2E3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR2E3

Gene Alias:
ESCS, NR2E3, PNR, rd7, RNR, RP37

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10002, 100365683, 23958

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.15 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9QXZ7, Q9Y5X4

Gene Symbols:
Nr2e3

Immunogen:
NR2E3 Fusion Protein Ag5503

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG