50-173-0059

TMP21 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-0059-Each-of-1 In Stock ₹ 42,443.75

50-173-0059 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

TMP21

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TMED10

Gene Alias

P24(DELTA), p24delta, S31I125, S31III125, TMED10, Tmp 21 I, TMP21, Transmembrane protein Tmp21

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10972, 68581, 84599

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.19 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P49755, Q63584, Q9D1D4

Gene Symbols

Tmed10

Immunogen

TMP21 Fusion Protein Ag7347

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
  • More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
  • The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
  • Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer′s disease
  • Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
  • Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.

Compare Similar Items

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Proteintech Group Inc

50-173-0059

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Antigen:
TMP21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMED10

Gene Alias:
P24(DELTA), p24delta, S31I125, S31III125, TMED10, Tmp 21 I, TMP21, Transmembrane protein Tmp21

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10972, 68581, 84599

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.19 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P49755, Q63584, Q9D1D4

Gene Symbols:
Tmed10

Immunogen:
TMP21 Fusion Protein Ag7347

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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50-173-0060

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Antigen:
B4GALT4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
B4GALT4

Gene Alias:
B4Gal T4, B4GALT4, Beta 1,4 GalTase 4, beta4Gal T4

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
303923, 56375, 8702

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O60513, Q66HH1, Q9JJ04

Gene Symbols:
B4galt4

Immunogen:
B4GALT4 Fusion Protein Ag7348

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0061

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Antigen:
IFIT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFIT3

Gene Alias:
CIG 49, CIG49, GARG 49, IFI 60K, IFI60, IFIT 3, IFIT 4, IFIT3, IFIT4, IRG2, ISG 60, ISG60, RIG G

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3437

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O14879

Gene Symbols:
IFIT3

Immunogen:
IFIT3 Fusion Protein Ag7349

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0062

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Antigen:
KAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM28

Gene Alias:
KAP 1, KAP1, KRAB associated protein 1, KRAB interacting protein 1, KRIP 1, Nuclear corepressor KAP 1, RING finger protein 96, RNF96, TF1B, TIF1 beta, TIF1B, TRIM28, tripartite motif containing 28

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10155, 116698, 21849

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O08629, Q13263, Q62318

Gene Symbols:
TRIM28

Immunogen:
KAP1 Fusion Protein Ag7350

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG