50-173-0182

RIPK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-0182-Each-of-1 In Stock ₹ 42,443.75

50-173-0182 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

RIPK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RIPK2

Gene Alias

CARD3, CARDIAK, CCK, GIG30, Receptor interacting protein 2, RICK, RIP 2, RIP2, RIPK2

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

192656, 362491, 8767

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

0.13 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O43353, P58801

Gene Symbols

Ripk2

Immunogen

RIPK2 Fusion Protein Ag0909

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses
  • Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains
  • Contributes to the tyrosine phosphorylation of the guanine exchange factor ARHGEF2 through Src tyrosine kinase leading to NF-kappaB activation by NOD2
  • Once recruited, RIPK2 autophosphorylates and undergoes ′Lys-63′-linked polyubiquitination by E3 ubiquitin ligases XIAP, BIRC2 and BIRC3
  • The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces ′Lys-63′-linked polyubiquitination of IKBKG/NEMO and subsequent activation of IKBKB/IKKB
  • In turn, NF-kappa-B is released from NF-kappa-B inhibitors and translocates into the nucleus where it activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
  • Plays also a role during engagement of the T-cell receptor (TCR) in promoting BCL10 phosphorylation and subsequent NF-kappa-B activation.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-173-0182

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Antigen:
RIPK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIPK2

Gene Alias:
CARD3, CARDIAK, CCK, GIG30, Receptor interacting protein 2, RICK, RIP 2, RIP2, RIPK2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
192656, 362491, 8767

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O43353, P58801

Gene Symbols:
Ripk2

Immunogen:
RIPK2 Fusion Protein Ag0909

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0183

--


Antigen:
COX8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COX8A

Gene Alias:
COX, COX8, COX8 2, COX8A, COX8L, VIII, VIII L

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12868, 1351

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P10176, Q64445

Gene Symbols:
COX8A

Immunogen:
COX8A Fusion Protein Ag2885

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0185

--


Antigen:
GLRB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLRB

Gene Alias:
GLRB, Glycine receptor subunit beta, glycine receptor, beta

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14658, 25456, 2743

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P20781, P48167, P48168

Gene Symbols:
GLRB

Immunogen:
GLRB Fusion Protein Ag4429

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0186

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Antigen:
RBM17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBM17

Gene Alias:
45 kDa splicing factor, RBM17, RNA binding motif protein 17, SPF45, Splicing factor 45

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
291295, 76938, 84991

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.15 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8JZX4, Q96I25

Gene Symbols:
Rbm17

Immunogen:
RBM17 Fusion Protein Ag0985

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG