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50-173-0518

C4BPB Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-173-0518-Each-of-1 In Stock ₹ 42,443.75

50-173-0518 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

C4BPB

Classification

Polyclonal

Conjugate

Unconjugated

Gene

C4BPB

Gene Alias

C4b binding protein beta chain, C4BP, C4BPB

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12270, 725

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.17 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P20851

Gene Symbols

C4BPB, C4bp-ps1

Immunogen

C4BPB Fusion Protein Ag8587

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • C4BP is composed of two polypeptides (alpha and beta chains), which have molecular weights of 70 and 45 kDa, respectively
  • This polyclonal antibody is raised against the C4BP beta chain (C4BPB)
  • Complement component 4-binding protein (C4BP) is a plasma glycoprotein that inhibits the classical pathway of complement activation, which is mediated through antibody targeting of foreign antigen
  • Structurally, C4BP is a disulfide linked, multimeric protein that is composed of seven alpha chains and one beta chain
  • C4BP functions as a cofactor for C3beta inactivator in the cleavage of C3beta, and accelerates the decay of C4betaC2alpha (C3 convertase) by acting as a cofactor in the cleavage of C4beta by factor I
  • Streptococcal strains that express Ig-binding cell surface molecules, which are members of the M protein family, can bind to overlapping C4beta binding sites in C4BP and therefore, interfere with the classical pathway of complement activation
  • Bacteria-bound C4BP may be an evolved mechanism that downregulates complement activation in the bacterial host microenvironment, thereby reducing the occurrences of bacterial opsonization and phagocytosis.

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Img

Proteintech Group Inc

50-173-0518

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Antigen:
C4BPB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C4BPB
Gene Alias:
C4b binding protein beta chain, C4BP, C4BPB
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12270, 725
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.17 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P20851
Gene Symbols:
C4BPB, C4bp-ps1
Immunogen:
C4BPB Fusion Protein Ag8587
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG

Img

Proteintech Group Inc

50-173-0523

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Antigen:
PLA2G1B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PLA2G1B
Gene Alias:
Group IB phospholipase A2, Phospholipase A2, PLA2, PLA2A, PLA2G1B, PPLA2
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18778, 29526, 5319
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.33 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P04054, P04055, Q9Z0Y2
Gene Symbols:
PLA2G1B
Immunogen:
PLA2G1B Fusion Protein Ag8603
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

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Proteintech Group Inc

50-173-0525

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Antigen:
TGM4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TGM4
Gene Alias:
Fibrinoligase, hTGP, Prostate transglutaminase, TG(P), TGase 4, TGase P, TGM4, TGP, Transglutaminase 4, transglutaminase 4 (prostate), Transglutaminase P
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
331046, 7047
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.13 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P49221, Q8BZH1
Gene Symbols:
Tgm4
Immunogen:
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Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG

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Proteintech Group Inc

50-173-0533

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Antigen:
CYTL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CYTL1
Gene Alias:
C17, C4orf4, CYTL1, cytokine like 1, Cytokine like protein 1, Protein C17
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
231162, 498392, 54360
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
0.18 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9NRR1
Gene Symbols:
CYTL1
Immunogen:
CYTL1 Fusion Protein Ag3977
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG