50-173-0869

dGK Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-0869-Each-of-1 In Stock ₹ 42,443.75

50-173-0869 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

dGK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DGUOK

Gene Alias

Deoxyguanosine kinase, dGK, DGUOK

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1716, 27369, 297389

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.18 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q16854, Q9QX60

Gene Symbols

Dguok

Immunogen

dGK Fusion Protein Ag9361

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Mitochondrial deoxyguanosine kinase (DGUOK) is required for the phosphorylation of several deoxyribonucleosides and certain purine deoxykribonucleoside analogs widely employed as antiviral and chemotherapeutic agents
  • Purine deoxyribonucleoside analogs are extensively used in treatment of lymphoproliferative disorders
  • These compounds are administered as pro-drugs, and their efficiency is dependent on intracellular phosphorylation to the corresponding triphosphates
  • In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predomitly by 2 deoxyribonucleoside kinases: cytosolic deoxycytidine kinase (DCK) and mitochondrial deoxyguanosine kinase (DGUOK also known as DGK)
  • DGUOK expression is ubiquitous, with highest levels in muscle, brain, liver and lymphoid tissues
  • Defects in DGUOK are a cause of mitochondrial DNA depletion syndrome (MDS)
  • MDS is a clinically heterogeneous group of disorders characterized by a reduction in mitochondrial DNA (mtDNA) copy number
  • Primary mtDNA depletion is inherited as an autosomal recessive trait and may affect single organs, typically muscle or liver, or multiple tissues.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-173-0869

--


Antigen:
dGK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DGUOK

Gene Alias:
Deoxyguanosine kinase, dGK, DGUOK

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1716, 27369, 297389

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q16854, Q9QX60

Gene Symbols:
Dguok

Immunogen:
dGK Fusion Protein Ag9361

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0870

--


Antigen:
GCAT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GCAT

Gene Alias:
AKB ligase, Aminoacetone synthase, GCAT, Glycine acetyltransferase, KBL

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23464, 26912, 366959

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75600, O88986

Gene Symbols:
Gcat

Immunogen:
GCAT Fusion Protein Ag9367

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0872

--


Antigen:
Placental lactogen

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CSH2

Gene Alias:
Choriomammotropin, CS 2, CSB, CSH1, CSH2, hCS B, Lactogen, PL, Placental lactogen

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1443

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P0DML3

Gene Symbols:
CSH2

Immunogen:
Placental lactogen Fusion Protein Ag9412

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0873

--


Antigen:
RAB30

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAB30

Gene Alias:
RAB30, Ras related protein Rab 30

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27314, 308821

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q15771

Gene Symbols:
Rab30

Immunogen:
RAB30 Fusion Protein Ag9444

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG