50-173-1427
AFAP1L2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-1427-Each-of-1 | In Stock | ₹ 42,443.75 |
50-173-1427 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
AFAP1L2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AFAP1L2
Gene Alias
AFAP1 like protein 2, AFAP1L2, KIAA1914, XB130
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
226250, 292130, 84632
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.13 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q5DTU0, Q8N4X5
Gene Symbols
AFAP1L2
Immunogen
AFAP1L2 Fusion Protein Ag10966
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- AFAP1L2, also known as XB130, is structurally similar to actin-filament-associated protein (AFAP), containing several SH2- and SH3-binding motifs, two pleckstrin homology domains, a coiled-coil region, and many potential phosphorylation sites
- It interacts with and is phosphorylated by c-Src tyrosine kinase
- Suppression of AFAP1L2 via siRNA reduced Src activity, IL-8 production, EGF-induced phosphorylation of Akt and GSK3beta, and altered cell cycles in human lung epithelial cells suggesting that AFAP1L2 plays a role as an adaptor in the regulation of Src signal transduction and multiple cellular functions
- Recent experiments have shown that AFAP1L2 is highly expressed in thyroid and is the substrate RET/PTC kinase, a thyroid-specific kinase that plays a pathogenic role in papillary thyroid cancer
- Down-regulation of AFAP1L2 in these cancer cells reduced Akt activity, inhibiting cell-cycle progression and cancer cell survival in suspension, indicating that AFAP1L2 may be a valuable target in thyroid cancer therapy
- At least four isoforms of AFAP1L2 are known to exist.
Compare Similar Items
Show Difference
Antigen: AFAP1L2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AFAP1L2
Gene Alias: AFAP1 like protein 2, AFAP1L2, KIAA1914, XB130
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 226250, 292130, 84632
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.13 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q5DTU0, Q8N4X5
Gene Symbols: AFAP1L2
Immunogen: AFAP1L2 Fusion Protein Ag10966
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AFAP1L2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AFAP1L2
Gene Alias:
AFAP1 like protein 2, AFAP1L2, KIAA1914, XB130
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
226250, 292130, 84632
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.13 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q5DTU0, Q8N4X5
Gene Symbols:
AFAP1L2
Immunogen:
AFAP1L2 Fusion Protein Ag10966
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZFP64
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZFP64
Gene Alias: Zfp 64, ZFP64, Zinc finger protein 338, ZNF338
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22722, 311661, 55734
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 0.17 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q99KE8, Q9NPA5
Gene Symbols: Zfp64
Immunogen: ZFP64 Fusion Protein Ag10971
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ZFP64
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZFP64
Gene Alias:
Zfp 64, ZFP64, Zinc finger protein 338, ZNF338
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22722, 311661, 55734
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.17 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q99KE8, Q9NPA5
Gene Symbols:
Zfp64
Immunogen:
ZFP64 Fusion Protein Ag10971
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CBFA2T3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CBFA2T3
Gene Alias: CBFA2T3, ETO2, hMTG16, MTG16, MTG8 related protein 2, MTGR2, Protein CBFA2T3, ZMYND4
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12398, 361431, 863
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 0.21 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: O54972, O75081
Gene Symbols: Cbfa2t3
Immunogen: CBFA2T3 Fusion Protein Ag9265
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CBFA2T3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CBFA2T3
Gene Alias:
CBFA2T3, ETO2, hMTG16, MTG16, MTG8 related protein 2, MTGR2, Protein CBFA2T3, ZMYND4
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12398, 361431, 863
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.21 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
O54972, O75081
Gene Symbols:
Cbfa2t3
Immunogen:
CBFA2T3 Fusion Protein Ag9265
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: DNMBP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNMBP
Gene Alias: DNMBP, dynamin binding protein, KIAA1010, Scaffold protein Tuba, TUBA
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23268, 309362, 71972
Content And Storage: -20°C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.23 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q6TXD4, Q6XZF7
Gene Symbols: Dnmbp
Immunogen: DNMBP Fusion Protein Ag10973
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DNMBP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNMBP
Gene Alias:
DNMBP, dynamin binding protein, KIAA1010, Scaffold protein Tuba, TUBA
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23268, 309362, 71972
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.23 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q6TXD4, Q6XZF7
Gene Symbols:
Dnmbp
Immunogen:
DNMBP Fusion Protein Ag10973
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG