50-173-1526

MKNK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-1526-Each-of-1 In Stock ₹ 42,443.75

50-173-1526 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

MKNK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MKNK2

Gene Alias

GPRK7, MKNK2, MNK2

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17347, 2872, 299618

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

Q5U2N4, Q8CDB0, Q9HBH9

Gene Symbols

MKNK2

Immunogen

MKNK2 Fusion Protein Ag10546

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • MAP kinase-interacting kinase 1 (Mnk1) and Mnk2, members of the Ser/Thr protein kinase family, bind tightly to the growth factor-regulated MAP kinases, Erk1 and Erk2
  • Erk and p38 phosphorylate MNK1 and Mnk2, which stimulates their in vitro kinase activity toward a substrate, eukaryotic initiation factor-4E (eIF-4E)
  • Overexpression of Mnk2 results in increased phosphorylation of endogenous eIF-4E, showing that it can act as an eIF-4E kinase in vivo
  • Mnk2 may play a role in the response to environmental stress and cytokines
  • This ubiquitiously expressed protein appears to regulate transcription by phosphorylating eIF-4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap
  • Expression of active mutants of MNK1 and MNK2 in 293 cells diminishes cap-dependent translation relative to cap-independent translation in a transient reporter assay
  • Human Mnk2 is homologous to murine Mnk2 (approximately 94% identical) and human Mnk1 (71% identical)
  • In vitro phosphorylation studies show that Mnk2 is a significantly better substrate than Mnk1 for extracellular signal-regulated kinase 2 (Erk2), p38MAPKalpha, and p38MAPKbeta
  • Mnk2 has also been shown to interact with the C-terminal regions of eIF-4G1 and eIF-4G2.

Compare Similar Items

Show Difference

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Proteintech Group Inc

50-173-1526

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Antigen:
MKNK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MKNK2

Gene Alias:
GPRK7, MKNK2, MNK2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17347, 2872, 299618

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q5U2N4, Q8CDB0, Q9HBH9

Gene Symbols:
MKNK2

Immunogen:
MKNK2 Fusion Protein Ag10546

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Proteintech Group Inc

50-173-1528

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Antigen:
CHDH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHDH

Gene Alias:
CDH, CHD, CHDH, Choline dehydrogenase

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
218865, 290551, 55349

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q6UPE0, Q8BJ64, Q8NE62

Gene Symbols:
Chdh

Immunogen:
CHDH Fusion Protein Ag10614

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-1529

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Antigen:
SPATA16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPATA16

Gene Alias:
NYD SP12, SPATA16, spermatogenesis associated 16

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
294932, 70862, 83893

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.19 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q8C636, Q9BXB7

Gene Symbols:
Spata16

Immunogen:
SPATA16 Fusion Protein Ag10637

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Antigen:
LY6D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LY6D

Gene Alias:
E48, E48 antigen, Ly 6D, LY6D, Lymphocyte antigen 6D

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17068, 8581

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P35459, Q14210

Gene Symbols:
Ly6d

Immunogen:
LY6D Fusion Protein Ag10714

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG