50-173-1872

MDMX Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-1872-Each-of-1 In Stock ₹ 42,443.75

50-173-1872 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

MDMX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MDM4

Gene Alias

Double minute 4 protein, HDMX, Mdm2 like p53 binding protein, MDM4, MDMX, MRP1, p53 binding protein Mdm4, Protein Mdm4, Protein Mdmx

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17248, 304798, 4194

Content And Storage

-20°C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

0.23 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O15151, O35618, Q5XIN1

Gene Symbols

Mdm4

Immunogen

MDMX Fusion Protein Ag12319

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The MDM2 protein is the primary regulator of p53 protein stability
  • MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2
  • The gene that encodes MDMX (also designated MDM4) is a target for amplification in maligt gliomas
  • ARF interacts with MDMX to sequester MDMX within the nucleolus
  • This sequestration of MDMX by ARF results in an increase in p53 transactivation
  • In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation
  • Like MDM2, MDMX also binds p73 and stabilizes the level of p73
  • Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-173-1872

--


Antigen:
MDMX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MDM4

Gene Alias:
Double minute 4 protein, HDMX, Mdm2 like p53 binding protein, MDM4, MDMX, MRP1, p53 binding protein Mdm4, Protein Mdm4, Protein Mdmx

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17248, 304798, 4194

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O15151, O35618, Q5XIN1

Gene Symbols:
Mdm4

Immunogen:
MDMX Fusion Protein Ag12319

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-1873

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Antigen:
EIF4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4B

Gene Alias:
EIF 4B, EIF4B, PRO1843

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1975, 300253, 75705

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Concentration:
0.45 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P23588, Q8BGD9

Gene Symbols:
Eif4b

Immunogen:
EIF4B Fusion Protein Ag12325

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-1874

--


Antigen:
SNX5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SNX5

Gene Alias:
SNX5, sorting nexin 5

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27131, 296199, 69178

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
B1H267, Q9D8U8, Q9Y5X3

Gene Symbols:
Snx5

Immunogen:
SNX5 Fusion Protein Ag12330

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-1875

--


Antigen:
ING1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ING1

Gene Alias:
ING1, Inhibitor of growth protein 1, p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26356, 306626, 3621

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q9QXV3, Q9UK53

Gene Symbols:
Ing1

Immunogen:
ING1 Fusion Protein Ag12338

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG