50-173-2063

TRPC6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-2063-Each-of-1 In Stock ₹ 42,443.75

50-173-2063 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

TRPC6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TRPC6

Gene Alias

FSGS2, Transient receptor protein 6, TRP 6, TRP6, TRPC6

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22068, 7225, 89823

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.23 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q61143, Q9Y210

Gene Symbols

TRPC6

Immunogen

TRPC6 Fusion Protein Ag12976

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Trpc6 forms a receptor-activated calcium channel in the cell membrane
  • The Trpc6 channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system
  • Activation of the Trpc6 channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium
  • Defects in the Trpc6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)
  • Further, Trpc6 is a member of the mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family
  • The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types
  • Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors
  • When expressed in transfected cells, Trpc6 acts as a non-selective store-independent receptor-activated cation channel
  • Trpc6 is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation
  • There is increasing evidence that Trpc6 encodes endogenous DAG-activated receptor-operated cation channels in vivo
  • Diseases associated with TRPC6 include Glomerulosclerosis, Focal Segmental, 2 and Focal Segmental Glomerulosclerosis.

Compare Similar Items

Show Difference

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Proteintech Group Inc

50-173-2063

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Antigen:
TRPC6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPC6

Gene Alias:
FSGS2, Transient receptor protein 6, TRP 6, TRP6, TRPC6

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22068, 7225, 89823

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q61143, Q9Y210

Gene Symbols:
TRPC6

Immunogen:
TRPC6 Fusion Protein Ag12976

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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50-173-2064

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Antigen:
MMP28

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MMP28

Gene Alias:
EPILYSIN, matrix metallopeptidase 28, Matrix metalloproteinase 28, MM28, MMP 28, MMP28

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
118453, 303384, 79148

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H239

Gene Symbols:
MMP28

Immunogen:
MMP28 Fusion Protein Ag12980

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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Antigen:
TM4SF5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TM4SF5

Gene Alias:
TM4SF5

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
303256, 75604, 9032

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.3 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O14894

Gene Symbols:
Tm4sf5

Immunogen:
TM4SF5 Fusion Protein Ag13004

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Antigen:
GADL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GADL1

Gene Alias:
GADL1, glutamate decarboxylase like 1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
339896, 367181, 73748

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.14 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q6ZQY3, Q80WP8

Gene Symbols:
GADL1

Immunogen:
GADL1 Fusion Protein Ag13005

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG