50-173-2116
PHD3 Rabbit anti-Human, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-2116-Each-of-1 | In Stock | ₹ 44,150.23 |
50-173-2116 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
PHD3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EGLN3
Gene Alias
Egl nine homolog 3, EGLN3, HIF PH3, HIF prolyl hydroxylase 3, HIFPH3, HPH 1, HPH 3, PHD3
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
112399
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.27 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9H6Z9
Gene Symbols
EGLN3
Immunogen
PHD3 Fusion Protein Ag13197
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- HIF prolyl hydroxylase 3 is a prolyl hydroxylase that modifies HIF-alpha
- Classic prolyl hydroxylases are found in the endoplasmic reticulum and modify collagen, whereas HIF is an intracellular protein and the HPH sites do not resemble those modifying collagen
- HIF is a transcriptional complex that plays a critical role in oxygen homeostasis
- HPH is an essential component of the pathway through which cells sense oxygen
- In the presence of oxygen, HPHs convert specific prolyl residues in HIF-alpha to hydroxyproline, leading to HIF-alpha destruction
- Low oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF is stable and there is increased angiogenesis
- HIF prolyl hydroxylase 1, specifically, catalyzes the posttranslational formation of 4-hydroxyproline in HIF alpha proteins
- It hydroxylates HIF-1 alpha at Pro (564) and HIF-2 alpha
- It targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex
- It may also play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissues, promoting cell death through a caspase-dependent mechanism.
Compare Similar Items
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Antigen: PHD3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EGLN3
Gene Alias: Egl nine homolog 3, EGLN3, HIF PH3, HIF prolyl hydroxylase 3, HIFPH3, HPH 1, HPH 3, PHD3
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 112399
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.27 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9H6Z9
Gene Symbols: EGLN3
Immunogen: PHD3 Fusion Protein Ag13197
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PHD3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EGLN3
Gene Alias:
Egl nine homolog 3, EGLN3, HIF PH3, HIF prolyl hydroxylase 3, HIFPH3, HPH 1, HPH 3, PHD3
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
112399
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.27 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9H6Z9
Gene Symbols:
EGLN3
Immunogen:
PHD3 Fusion Protein Ag13197
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CD24
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD24
Gene Alias: CD24, CD24 molecule, CD24A, Signal transducer CD24
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100133941, 12484
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 0.18 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P24807, P25063
Gene Symbols: CD24
Immunogen: CD24 Fusion Protein Ag11679
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD24
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD24
Gene Alias:
CD24, CD24 molecule, CD24A, Signal transducer CD24
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100133941, 12484
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.18 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P24807, P25063
Gene Symbols:
CD24
Immunogen:
CD24 Fusion Protein Ag11679
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: AP3B2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AP3B2
Gene Alias: AP 3 complex subunit beta 2, AP3B2, Beta 3B adaptin, NAPTB
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11775, 308777, 8120
Content And Storage: -20°C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.27 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: Q13367, Q9JME5
Gene Symbols: Ap3b2
Immunogen: AP3B2 Fusion Protein Ag12861
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AP3B2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AP3B2
Gene Alias:
AP 3 complex subunit beta 2, AP3B2, Beta 3B adaptin, NAPTB
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11775, 308777, 8120
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.27 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q13367, Q9JME5
Gene Symbols:
Ap3b2
Immunogen:
AP3B2 Fusion Protein Ag12861
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TBC1D22A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBC1D22A
Gene Alias: C22orf4, HSC79E021, TBC1 domain family member 22A, TBC1 domain family, member 22A, TBC1D22A
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 223754, 25771, 689443
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.17 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8R5A6, Q8WUA7
Gene Symbols: Tbc1d22a
Immunogen: TBC1D22A Fusion Protein Ag12942
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TBC1D22A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBC1D22A
Gene Alias:
C22orf4, HSC79E021, TBC1 domain family member 22A, TBC1 domain family, member 22A, TBC1D22A
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
223754, 25771, 689443
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.17 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8R5A6, Q8WUA7
Gene Symbols:
Tbc1d22a
Immunogen:
TBC1D22A Fusion Protein Ag12942
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG