50-173-2973
APOB Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-2973-Each-of-1 | In Stock | ₹ 42,443.75 |
50-173-2973 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
APOB
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APOB
Gene Alias
Apo B 100, Apo B 48, APOB, ApoB100, Apolipoprotein B, Apolipoprotein B 100, FLDB
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
238055, 338
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.18 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
E9Q414, P04114
Gene Symbols
APOB
Immunogen
Peptide
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- This antibody recognizes both of ApoB-48 and ApoB-100
- Apolipoprotein B (apo B) in human plasma is a major protein of low density lipoproteins (LDL) with a molecular mass of approximately 260-500 kDa
- Apolipoprotein B binds to specific receptors on cell membranes and is involved in removal of LDL and very low density lipoprotein (VLDL) cholesterol from circulation
- Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood
- LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearance of cholesterol from the circulation
- In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36
- Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described
- MDA-oxidized LDL appear to be different from LDL oxidized by other means
- Apolipoprotein B is mostly synthesized in the liver, and is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a)
- Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis
- Normal plasma apolipoprotein B levels are around 800mg/L
- Apolipoprotein B occurs in plasma as two main isoforms, apoB-48 and apoB-100
- The intestinal and the hepatic forms of Apolipoprotein B are encoded by a single gene from a single, very long mRNA
- The two isoforms share a common N-terminal sequence
- The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination
- Mutations in the Apolipoprotein B gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective Apolipoprotein B, diseases affecting plasma cholesterol and Apolipoprotein B levels.
Compare Similar Items
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Antigen: APOB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APOB
Gene Alias: Apo B 100, Apo B 48, APOB, ApoB100, Apolipoprotein B, Apolipoprotein B 100, FLDB
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 238055, 338
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.18 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: E9Q414, P04114
Gene Symbols: APOB
Immunogen: Peptide
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
APOB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APOB
Gene Alias:
Apo B 100, Apo B 48, APOB, ApoB100, Apolipoprotein B, Apolipoprotein B 100, FLDB
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
238055, 338
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.18 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
E9Q414, P04114
Gene Symbols:
APOB
Immunogen:
Peptide
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PI3K p110(beta)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PIK3CB
Gene Alias: p110 BETA, PI3 Kinase p110 beta, PI3 kinase subunit beta, PI3K, PI3K beta, PI3K p110(beta), PI3Kbeta, PI3KCB, PIK3C1, PIK3CB, PtdIns 3 kinase subunit beta
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5291
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.17 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P42338
Gene Symbols: PIK3CB
Immunogen: Peptide
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PI3K p110(beta)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PIK3CB
Gene Alias:
p110 BETA, PI3 Kinase p110 beta, PI3 kinase subunit beta, PI3K, PI3K beta, PI3K p110(beta), PI3Kbeta, PI3KCB, PIK3C1, PIK3CB, PtdIns 3 kinase subunit beta
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5291
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.17 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P42338
Gene Symbols:
PIK3CB
Immunogen:
Peptide
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: AIM2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AIM2
Gene Alias: absent in melanoma 2, AIM2, PYHIN4
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 304987, 383619, 9447
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.57 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O14862, Q91VJ1
Gene Symbols: Aim2
Immunogen: AIM2 Fusion Protein Ag14520
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AIM2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AIM2
Gene Alias:
absent in melanoma 2, AIM2, PYHIN4
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
304987, 383619, 9447
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.57 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O14862, Q91VJ1
Gene Symbols:
Aim2
Immunogen:
AIM2 Fusion Protein Ag14520
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ORAI2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ORAI2
Gene Alias: C7orf19, CBCIP2, ORAI2, Protein orai 2, TMEM142B, Transmembrane protein 142B
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 269717, 80228
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.17 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8BH10, Q96SN7
Gene Symbols: ORAI2
Immunogen: ORAI2 Fusion Protein Ag14540
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ORAI2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ORAI2
Gene Alias:
C7orf19, CBCIP2, ORAI2, Protein orai 2, TMEM142B, Transmembrane protein 142B
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
269717, 80228
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.17 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8BH10, Q96SN7
Gene Symbols:
ORAI2
Immunogen:
ORAI2 Fusion Protein Ag14540
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG