50-173-3402

RNF168 Rabbit anti-Human, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-3402-Each-of-1 In Stock ₹ 42,443.75

50-173-3402 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

RNF168

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RNF168

Gene Alias

ring finger protein 168, RNF168

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

165918

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Concentration

0.49 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8IYW5

Gene Symbols

RNF168

Immunogen

RNF168 Fusion Protein Ag16055

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • RNF168 was identified as a chromatin-associated RING finger protein that acts as a ubiquitin ligase both in vitro and in vivo
  • RNF168 targets histones H2A and H2AX, but not H2B, forming K63 polyubiquitin chains
  • Upon formation of DNA double strand breaks, RNF168 is recruited to the site of DNA damage where it co-localizes with -gammaH2AX and 53BP1 in an RNF8-dependent manner
  • This localization of RNF168 increases the local concentration of ubiquinated proteins to the threshold required for retention of the proteins 53BP1 and BRCA1, facilitating the downstream signaling cascade
  • Thus, RNF168 defines a new pathway demonstrating a functional cooperation between E3 ligases in genome maintece
  • At least three isoforms of RNF168 are known to exist.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-173-3402

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Antigen:
RNF168

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNF168

Gene Alias:
ring finger protein 168, RNF168

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
165918

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Concentration:
0.49 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8IYW5

Gene Symbols:
RNF168

Immunogen:
RNF168 Fusion Protein Ag16055

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-3403

--


Antigen:
RLBP1L2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLVS2

Gene Alias:
C6orf212, C6orf213, Clavesin 2, CLVS2, RLBP1L2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
134829, 215890, 361459

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
0.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
A6JUQ6, Q5SYC1, Q8BG92

Gene Symbols:
Clvs2

Immunogen:
RLBP1L2 Fusion Protein Ag16061

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-3404

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Antigen:
SGSM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SGSM1

Gene Alias:
KIAA1941, RUTBC2, SGSM1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
129049, 52850

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.47 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q2NKQ1, Q8BPQ7

Gene Symbols:
Sgsm1

Immunogen:
SGSM1 Fusion Protein Ag16070

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-3405

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Antigen:
ERC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERC2

Gene Alias:
CAST, CAST1, ELKSL, ERC protein 2, ERC2, KIAA0378, SPBC110, Spc110

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238988, 259269, 26059

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
0.57 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O15083, Q6PH08, Q8K3M6

Gene Symbols:
Erc2

Immunogen:
ERC2 Fusion Protein Ag16080

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG