50-173-3990

SUPT6H Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-3990-Each-of-1 In Stock ₹ 42,443.75

50-173-3990 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

SUPT6H

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SUPT6H

Gene Alias

emb 5, hSPT6, KIAA0162, SPT6, SPT6H, SUPT6H, Tat cotransactivator 2 protein, Tat CT2 protein

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20926, 303281, 6830

Content And Storage

-20°C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

0.29 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q62383, Q7KZ85

Gene Symbols

SUPT6H

Immunogen

SUPT6H Fusion Protein Ag19426

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • This antibody specifically recognizes the 230 kDa phosphorylated SUPT6H protein
  • Transcription elongation factor which binds histone H3 and plays a key role in the regulation of transcription elongation and mRNA processing
  • Enhances the transcription elongation by RNA polymerase II (RNAPII) and is also required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat
  • Besides chaperoning histones in transcription, acts to transport and splice mRNA by forming a complex with IWS1 and the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A)
  • The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2), to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription
  • SUPT6H via its association with SETD1A, regulates both class-switch recombination and somatic hypermutation through formation of H3K4me3 epigenetic marks on activation-induced cytidine deaminase (AICDA) target loci
  • Promotes the activation of the myogenic gene program by entailing erasure of the repressive H3K27me3 epigenetic mark through stabilization of the chromatin interaction of the H3K27 demethylase KDM6A.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-173-3990

--


Antigen:
SUPT6H

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SUPT6H

Gene Alias:
emb 5, hSPT6, KIAA0162, SPT6, SPT6H, SUPT6H, Tat cotransactivator 2 protein, Tat CT2 protein

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20926, 303281, 6830

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q62383, Q7KZ85

Gene Symbols:
SUPT6H

Immunogen:
SUPT6H Fusion Protein Ag19426

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-3991

--


Antigen:
CD99

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD99

Gene Alias:
12E7, CD99, CD99 antigen, CD99 molecule, E2 antigen, MIC2, MIC2X, MIC2Y, Protein MIC2, T cell surface glycoprotein E2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4267

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P14209

Gene Symbols:
CD99

Immunogen:
CD99 Fusion Protein Ag19461

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-3992

--


Antigen:
ACTA2/smooth muscle actin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ACTA2

Gene Alias:
a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, ACTA2 specific, Actin, aortic smooth muscle, ACTSA, ACTVS, Alpha actin 2, Alpha SMA, a-SMA

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11475, 59, 81633

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P62736, P62737, P62738

Gene Symbols:
ACTA2

Immunogen:
ACTA2/smooth muscle actin Fusion Protein Ag19481

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-3993

--


Antigen:
alpha Actin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ACTA1

Gene Alias:
ACTC, ACTC1, ACTC1 cardiac muscle 1, Actin, alpha cardiac muscle 1, actin, alpha, cardiac muscle 1, Alpha actin, Alpha cardiac actin, CMD1R, CMH11

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11459, 11464, 58, 70

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P68032, P68033, P68133, P68134

Gene Symbols:
ACTA1, ACTC1

Immunogen:
alpha Actin Fusion Protein Ag19482

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG