50-173-4174
MAP4K1 Rabbit anti-Human, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-4174-Each-of-1 | In Stock | ₹ 42,443.75 |
50-173-4174 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
MAP4K1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAP4K1
Gene Alias
HPK1, MAP4K1, MEK kinase kinase 1, MEKKK 1
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11184
Content And Storage
-20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
0.3 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q92918
Gene Symbols
MAP4K1
Immunogen
MAP4K1 Fusion Protein Ag20221
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The c-Jun amino-terminal kinases (JNKs)/stress-activated protein kinases (SAPKs) play a crucial role in stress responses in mammalian cells
- The mechanism underlying this pathway in the hematopoietic system is unclear, but it is a key in understanding the molecular basis of blood cell differentiation
- We have cloned a novel protein kinase, termed hematopoietic progenitor kinase 1 (HPK1), that is expressed predomitly in hematopoietic cells, including early progenitor cells
- HPK1 is related distantly to the p21(Cdc42/Rac1)-activated kinase (PAK) and yeast STE20 implicated in the mitogen-activated protein kinase (MAPK) cascade
- Expression of HPK1 activates JNK1 specifically, and it elevates strongly AP-1-mediated transcriptional activity in vivo
- HPK1 binds and phosphorylates MEKK1 directly, whereas JNK1 activation by HPK1 is inhibited by a domit-negative MEKK1 or MKK4/SEK mutant
- Interestingly, unlike PAK65, HPK1 does not contain the small GTPase Rac1/Cdc42-binding domain and does not bind to either Rac1 or Cdc42, suggesting that HPK1
- activation is Rac1/Cdc42-independent
- These results indicate that HPK1 is a novel functional activator of the JNK/SAPK signaling pathway.
Compare Similar Items
Show Difference
Antigen: MAP4K1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP4K1
Gene Alias: HPK1, MAP4K1, MEK kinase kinase 1, MEKKK 1
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11184
Content And Storage: -20°C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q92918
Gene Symbols: MAP4K1
Immunogen: MAP4K1 Fusion Protein Ag20221
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MAP4K1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP4K1
Gene Alias:
HPK1, MAP4K1, MEK kinase kinase 1, MEKKK 1
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11184
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q92918
Gene Symbols:
MAP4K1
Immunogen:
MAP4K1 Fusion Protein Ag20221
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CHPF N-terminal
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CHPF
Gene Alias: Chondroitin sulfate synthase 2, CHPF, CHSY2, CSS2
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 316533, 74241, 79586
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q6IQX7, Q8IZ52
Gene Symbols: Chpf
Immunogen: CHPF N-terminal Fusion Protein Ag20819
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CHPF N-terminal
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CHPF
Gene Alias:
Chondroitin sulfate synthase 2, CHPF, CHSY2, CSS2
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
316533, 74241, 79586
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q6IQX7, Q8IZ52
Gene Symbols:
Chpf
Immunogen:
CHPF N-terminal Fusion Protein Ag20819
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BCL3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BCL3
Gene Alias: B cell CLL/lymphoma 3, B cell lymphoma 3 protein, BCL3, D19S37, Proto oncogene BCL3
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 602
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.32 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P20749
Gene Symbols: BCL3
Immunogen: BCL3 Fusion Protein Ag21040
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
BCL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BCL3
Gene Alias:
B cell CLL/lymphoma 3, B cell lymphoma 3 protein, BCL3, D19S37, Proto oncogene BCL3
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
602
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.32 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P20749
Gene Symbols:
BCL3
Immunogen:
BCL3 Fusion Protein Ag21040
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MPEG1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MPEG1
Gene Alias: macrophage expressed 1, Macrophage gene 1 protein, MPEG1, Mpg 1, MPG1
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 219972
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 0.36 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q2M385
Gene Symbols: MPEG1
Immunogen: MPEG1 Fusion Protein Ag21055
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MPEG1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MPEG1
Gene Alias:
macrophage expressed 1, Macrophage gene 1 protein, MPEG1, Mpg 1, MPG1
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
219972
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.36 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q2M385
Gene Symbols:
MPEG1
Immunogen:
MPEG1 Fusion Protein Ag21055
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG