50-173-5302

MCU/CCDC109A Rabbit anti-Human, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-5302-Each-of-1 In Stock ₹ 42,443.75

50-173-5302 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

MCU/CCDC109A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MCU

Gene Alias

C10orf42, Calcium uniporter protein, CCDC109A, MCU

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

90550

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Concentration

0.35 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

Q8NE86

Gene Symbols

MCU

Immunogen

MCU/CCDC109A Fusion Protein Ag24733

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria
  • Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex)
  • Activity is regulated by MICU1 and MICU2
  • At low Ca(2+) levels MCU activity is down-regulated by MICU1 and MICU2; at higher Ca(2+) levels MICU1 increases MCU activity
  • Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways
  • Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes
  • While dispensable for baseline homeostatic cardiac function, acts as a key regulator of short-term mitochondrial calcium loading underlying a ′fight-or-flight′ response during acute stress: acts by mediating a rapid increase of mitochondrial calcium in pacemaker cells
  • participates in mitochondrial permeability transition during ischemia-reperfusion injury
  • Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake
  • Mitochondrial calcium uptake in skeletal muscle cells is involved in muscle size in adults
  • Regulates synaptic vesicle endocytosis kinetics in central nerve terminal
  • Involved in antigen processing and presentation.

Compare Similar Items

Show Difference

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Proteintech Group Inc

50-173-5302

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Antigen:
MCU/CCDC109A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MCU

Gene Alias:
C10orf42, Calcium uniporter protein, CCDC109A, MCU

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
90550

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
0.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q8NE86

Gene Symbols:
MCU

Immunogen:
MCU/CCDC109A Fusion Protein Ag24733

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-5303

--


Antigen:
CCDC21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CEP85

Gene Alias:
CCDC21, CEP85

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64793

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q6P2H3

Gene Symbols:
CEP85

Immunogen:
CCDC21 Fusion Protein Ag23636

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-5307

--


Antigen:
C1orf71

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNST

Gene Alias:
C1orf71, CNST, Consortin

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
163882, 226744

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.32 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q6PJW8, Q8CBC4

Gene Symbols:
CNST

Immunogen:
C1orf71 Fusion Protein Ag23732

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-5309

--


Antigen:
C19orf21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MISP

Gene Alias:
C19orf21, MISP, Mitotic interactor and substrate of PLK1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126353

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q8IVT2

Gene Symbols:
MISP

Immunogen:
C19orf21 Fusion Protein Ag23712

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG