50-173-5650

GLTSCR2 Rabbit anti-Human, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-173-5650-Each-of-1 In Stock ₹ 42,443.75

50-173-5650 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

GLTSCR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOP53

Gene Alias

GLTSCR2, p60, PICT 1, PICT1

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29997

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

0.33 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

Q9NZM5

Gene Symbols

NOP53

Immunogen

GLTSCR2 Fusion Protein Ag26358

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis
  • In ribosome biogenesis, may also play a role in rRNA transcription
  • Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions
  • DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and allow p53/TP53 activation
  • It may also positively regulate the function of p53/TP53 in cell cycle arrest and apoptosis through direct interaction, preventing its MDM2-dependent ubiquitin-mediated proteasomal degradation
  • Originally identified as a tumor suppressor, it may also play a role in cell proliferation and apoptosis by positively regulating the stability of PTEN, thereby antagonizing the PI3K-AKT/PKB signaling pathway
  • May also inhibit cell proliferation and increase apoptosis through its interaction with NF2
  • May negatively regulate NPM1 by regulating its nucleoplasmic localization, oligomerization and ubiquitin-mediated proteasomal degradation
  • Thereby, may prevent NPM1 interaction with MYC and negatively regulate transcription mediated by the MYC-NPM1 complex
  • May also regulate cellular aerobic respiration
  • In the cellular response to viral infection, may play a role in the attenuation of interferon-beta through the inhibition of DDX58/RIG-1.

Compare Similar Items

Show Difference

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Proteintech Group Inc

50-173-5650

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Antigen:
GLTSCR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOP53

Gene Alias:
GLTSCR2, p60, PICT 1, PICT1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29997

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q9NZM5

Gene Symbols:
NOP53

Immunogen:
GLTSCR2 Fusion Protein Ag26358

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-5651

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Antigen:
AP50

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AP2M1

Gene Alias:
Adaptin mu2, AP 2 complex subunit mu, AP 2 mu chain, AP2M1, AP50, CLAPM1, HA2 50 kDa subunit, KIAA0109, mu2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116563, 1173, 11773

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P84091, P84092, Q96CW1

Gene Symbols:
Ap2m1

Immunogen:
AP50 Fusion Protein Ag26059

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-5652

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Antigen:
ADAL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAL

Gene Alias:
ADAL, adenosine deaminase like

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
161823

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q6DHV7

Gene Symbols:
ADAL

Immunogen:
ADAL Fusion Protein Ag25949

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-5653

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Antigen:
CYSLTR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYSLTR1

Gene Alias:
CYSLT1, CYSLT1R, CYSLTR, CYSLTR1, HG55, HMTMF81, LTD4 receptor

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10800, 114099, 58861

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q924T8, Q99JA4, Q9Y271

Gene Symbols:
Cysltr1

Immunogen:
CYSLTR1 Fusion Protein Ag24961

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG