50-173-6265

CUL4B Mouse anti-Human, Rat, Clone: 4E10B10, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-6265-Each-of-1 In Stock ₹ 42,443.75

50-173-6265 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

CUL4B

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

Q13620

Host Species

Mouse

Purification Method

Caprylic Acid Precipitation

Regulatory Status

RUO

Gene ID (Entrez)

302502, 8450

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

4E10B10

Conjugate

Unconjugated

Gene

CUL4B

Gene Symbols

CUL4B

Immunogen

CUL4B Fusion Protein Ag3563

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG1

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Description

  • Cullin 4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
  • The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit
  • CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
  • Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage
  • Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication
  • Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression
  • Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism
  • Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-173-6265

--


Antigen:
CUL4B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q13620

Host Species:
Mouse

Purification Method:
Caprylic Acid Precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
302502, 8450

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4E10B10

Conjugate:
Unconjugated

Gene:
CUL4B

Gene Symbols:
CUL4B

Immunogen:
CUL4B Fusion Protein Ag3563

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Proteintech Group Inc

50-173-6266

--


Antigen:
FGF12

Classification:
Monoclonal

Concentration:
1.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P61328

Host Species:
Mouse

Purification Method:
Caprylic Acid Precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
2257

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Clone:
2F11A10

Conjugate:
Unconjugated

Gene:
FGF12

Gene Symbols:
FGF12

Immunogen:
FGF12 Fusion Protein Ag5046

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

Proteintech Group Inc

50-173-6267

--


Antigen:
ABCD1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P33897

Host Species:
Mouse

Purification Method:
Caprylic Acid Precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
215

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
1H8E5

Conjugate:
Unconjugated

Gene:
ABCD1

Gene Symbols:
ABCD1

Immunogen:
ABCD1 Fusion Protein Ag12757

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Proteintech Group Inc

50-173-6270

--


Antigen:
EPHA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P21709

Host Species:
Mouse

Purification Method:
Caprylic Acid Precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
2041

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
1B7C3

Conjugate:
Unconjugated

Gene:
EPHA1

Gene Symbols:
EPHA1

Immunogen:
Peptide

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1