50-173-6282

BCL2 Mouse anti-Human, Porcine, Clone: 4H8C6, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-6282-Each-of-1 In Stock ₹ 42,443.75

50-173-6282 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

BCL2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P10415

Gene Symbols

BCL2

Immunogen

BCL2 Fusion Protein Ag3508

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Porcine

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

4H8C6

Conjugate

Unconjugated

Gene

BCL2

Gene Alias

Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, BCL-2, Oncogene B cell leukemia 2

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100049703, 596

Content And Storage

-20°C

Form

Liquid

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Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-173-6282

--


Antigen:
BCL2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P10415

Gene Symbols:
BCL2

Immunogen:
BCL2 Fusion Protein Ag3508

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
4H8C6

Conjugate:
Unconjugated

Gene:
BCL2

Gene Alias:
Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, BCL-2, Oncogene B cell leukemia 2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100049703, 596

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6283

--


Antigen:
CD109

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q6YHK3

Gene Symbols:
CD109

Immunogen:
Peptide

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
2H8G7

Conjugate:
Unconjugated

Gene:
CD109

Gene Alias:
CD109, CD109 antigen, CD109 molecule, CPAMD7, p180, Platelet specific Gov antigen, r150, RP11 525G3.1

Host Species:
Mouse

Purification Method:
Caprylic Acid Precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
135228

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6284

--


Antigen:
CD34

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P28906

Gene Symbols:
CD34

Immunogen:
CD34 Fusion Protein Ag5996

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
3C8G12

Conjugate:
Unconjugated

Gene:
CD34

Gene Alias:
CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Caprylic Acid Precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
947

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6289

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Antigen:
Cyclin D1

Classification:
Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P24385, P25322

Gene Symbols:
CCND1

Immunogen:
Cyclin D1 Fusion Protein Ag0689

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
2G3G5

Conjugate:
Unconjugated

Gene:
CCND1

Gene Alias:
B cell lymphoma 1 protein, CCND1, cyclin D1, D11S287E, G1/S specific cyclin D1, PRAD1, PRAD1 oncogene, U21B31

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12443, 595

Content And Storage:
-20°C

Form:
Liquid