50-173-6443
Myocilin Mouse anti-Human, Mouse, Porcine, Rat, Clone: 4B1F6, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-6443-Each-of-1 | In Stock | ₹ 42,443.75 |
50-173-6443 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
Myocilin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O70624, Q99972, Q9R1J4
Gene Symbols
Myoc
Immunogen
Myocilin Fusion Protein Ag5492
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
4B1F6
Conjugate
Unconjugated
Gene
MYOC
Gene Alias
GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
17926, 397046, 4653, 81523
Content And Storage
-20°C
Form
Liquid
Description
- Myocilin is an extracellular protein expressed in the eye, including the retina, trabecular meshwork and ciliary body
- Myocilin can form homomultimers in vivo and can also associate with components of the ECM via interactions with the Hep II domain of FibroPVRL1
- In addition, myocilin interacts with myosin regulatory light chain, a component of the myosin motor protein complex
- This interaction implies a role for myocilin in the actomyosin system, linking myocilin to the functional status of the trabecular meshwork (TM), which is responsible for controlling the intraocular pressure (IOP)
- Alterations in functions of the TM may lead to IOP elevation and development of glaucoma, a major cause of blindness
- Myocilin is encoded by MYOC (also designated TIGR), a gene that maps to the GLC1A locus on chromosome 1q24.3 and is susceptible to mutations
- Mutations in the MYOC gene are specifically linked with primary open angle glaucoma (POAG), a blinding disease characterized by progressive loss of retinal ganglion cells.
Compare Similar Items
Show Difference
Antigen: Myocilin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O70624, Q99972, Q9R1J4
Gene Symbols: Myoc
Immunogen: Myocilin Fusion Protein Ag5492
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 4B1F6
Conjugate: Unconjugated
Gene: MYOC
Gene Alias: GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17926, 397046, 4653, 81523
Content And Storage: -20°C
Form: Liquid
Antigen:
Myocilin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O70624, Q99972, Q9R1J4
Gene Symbols:
Myoc
Immunogen:
Myocilin Fusion Protein Ag5492
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
4B1F6
Conjugate:
Unconjugated
Gene:
MYOC
Gene Alias:
GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17926, 397046, 4653, 81523
Content And Storage:
-20°C
Form:
Liquid
Antigen: GST Tag
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: __
Gene Symbols: __
Immunogen: __
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: __
Product Type: Antibody
Isotype: IgG2b
Applications: Immunoprecipitation, Western Blot
Clone: 3G12B10
Conjugate: Unconjugated
Gene: __
Gene Alias: GST, GST Tag
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Antigen:
GST Tag
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
__
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunoprecipitation, Western Blot
Clone:
3G12B10
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
GST, GST Tag
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid
Antigen: GFP tag
Classification: Monoclonal
Concentration: 1.42 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: __
Gene Symbols: __
Immunogen: GFP tag Fusion Protein Ag2128
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: __
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Clone: 1E10H7
Conjugate: Unconjugated
Gene: __
Gene Alias: CFP, eGFP, eYFP, GFP, GFP tag, YFP
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Antigen:
GFP tag
Classification:
Monoclonal
Concentration:
1.42 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
GFP tag Fusion Protein Ag2128
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
__
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Clone:
1E10H7
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
CFP, eGFP, eYFP, GFP, GFP tag, YFP
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid
Antigen: MBP tag
Classification: Monoclonal
Concentration: 1.35 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: __
Gene Symbols: __
Immunogen: MBP tag Fusion Protein Ag0942
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: __
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Clone: 4C6H4
Conjugate: Unconjugated
Gene: __
Gene Alias: Maltose Binding Protein, MBP, MBP Tag
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Antigen:
MBP tag
Classification:
Monoclonal
Concentration:
1.35 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
MBP tag Fusion Protein Ag0942
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
__
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Clone:
4C6H4
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Maltose Binding Protein, MBP, MBP Tag
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid