50-173-6539

CD22 Mouse anti-Human, Clone: 7A2F1, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-6539-Each-of-1 In Stock ₹ 42,443.75

50-173-6539 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

CD22

Classification

Monoclonal

Concentration

2.19 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P20273

Gene Symbols

CD22

Immunogen

CD22 Fusion Protein Ag17986

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

7A2F1

Conjugate

Unconjugated

Gene

CD22

Gene Alias

B cell receptor CD22, BL CAM, CD22, CD22 molecule, SIGLEC 2, SIGLEC2, T cell surface antigen Leu 14

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

933

Content And Storage

-20°C

Form

Liquid

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Description

  • CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
  • CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
  • CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
  • Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 preferentially binds to alpha2,6-linked sialic acid
  • The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
  • Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
  • CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predomice Hodgkin′s lymphoma, but negative in classical Hodgkin′s lymphoma.

Compare Similar Items

Show Difference

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Proteintech Group Inc

50-173-6539

--


Antigen:
CD22

Classification:
Monoclonal

Concentration:
2.19 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P20273

Gene Symbols:
CD22

Immunogen:
CD22 Fusion Protein Ag17986

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
7A2F1

Conjugate:
Unconjugated

Gene:
CD22

Gene Alias:
B cell receptor CD22, BL CAM, CD22, CD22 molecule, SIGLEC 2, SIGLEC2, T cell surface antigen Leu 14

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
933

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6541

--


Antigen:
PGM1

Classification:
Monoclonal

Concentration:
0.82 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P36871

Gene Symbols:
PGM1

Immunogen:
PGM1 Fusion Protein Ag7294

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
2G5A8

Conjugate:
Unconjugated

Gene:
PGM1

Gene Alias:
Glucose phosphomutase 1, PGM 1, PGM1, phosphoglucomutase 1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5236

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6547

--


Antigen:
SNRPD2

Classification:
Monoclonal

Concentration:
1.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P62316

Gene Symbols:
SNRPD2

Immunogen:
SNRPD2 Fusion Protein Ag7115

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
1F12B2

Conjugate:
Unconjugated

Gene:
SNRPD2

Gene Alias:
Sm D2, SMD2, snRNP core protein D2, SNRPD2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6633

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6549

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Antigen:
AFM

Classification:
Monoclonal

Concentration:
0.55 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O89020, P43652

Gene Symbols:
Afm

Immunogen:
AFM Fusion Protein Ag16866

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
2G9F6

Conjugate:
Unconjugated

Gene:
AFM

Gene Alias:
afamin, afamin/AFM, AFM, ALB2, ALBA, ALF, Alpha Alb, Alpha albumin

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
173, 280662

Content And Storage:
-20°C

Form:
Liquid