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50-173-6572

BBS5 Mouse anti-Human, Mouse, Clone: 4G8E12, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-173-6572-Each-of-1 In Stock ₹ 44,150.23

50-173-6572 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

BBS5

Classification

Monoclonal

Concentration

0.72 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8N3I7, Q9CZQ9

Gene Symbols

Bbs5

Immunogen

BBS5 Fusion Protein Ag6844

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

4G8E12

Conjugate

Unconjugated

Gene

BBS5

Gene Alias

Bardet Biedl syndrome 5, BBS5

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

129880, 72569

Content And Storage

-20°C

Form

Liquid

Description

  • The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia
  • The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function
  • This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome
  • Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane
  • Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane
  • The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation
  • Required for BBSome complex ciliary localization but not for the proper complex assembly.

Compare Similar Items

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Proteintech Group Inc

50-173-6572

--

Antigen:
BBS5
Classification:
Monoclonal
Concentration:
0.72 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8N3I7, Q9CZQ9
Gene Symbols:
Bbs5
Immunogen:
BBS5 Fusion Protein Ag6844
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
4G8E12
Conjugate:
Unconjugated
Gene:
BBS5
Gene Alias:
Bardet Biedl syndrome 5, BBS5
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
129880, 72569
Content And Storage:
-20°C
Form:
Liquid

Img

Proteintech Group Inc

50-173-6573

--

Antigen:
IFITM2
Classification:
Monoclonal
Concentration:
0.88 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q01629
Gene Symbols:
IFITM2
Immunogen:
__
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Western Blot
Clone:
3D5F7
Conjugate:
Unconjugated
Gene:
IFITM2
Gene Alias:
DSPA2c, IFITM2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
10581
Content And Storage:
-20°C
Form:
Liquid

Img

Proteintech Group Inc

50-173-6574

--

Antigen:
TRPC4AP
Classification:
Monoclonal
Concentration:
0.96 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8TEL6
Gene Symbols:
TRPC4AP
Immunogen:
TRPC4AP Fusion Protein Ag18772
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG3
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
2C10B1
Conjugate:
Unconjugated
Gene:
TRPC4AP
Gene Alias:
C20orf188, Protein TAP1, Protein TRUSS, Trp4 associated protein, Trpc4 associated protein, TRPC4AP, TRRP4AP, TRUSS
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
26133
Content And Storage:
-20°C
Form:
Liquid

Img

Proteintech Group Inc

50-173-6576

--

Antigen:
AEBP2
Classification:
Monoclonal
Concentration:
0.93 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q6ZN18
Gene Symbols:
AEBP2
Immunogen:
AEBP2 Fusion Protein Ag17905
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Porcine
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
7H2B11
Conjugate:
Unconjugated
Gene:
AEBP2
Gene Alias:
AE binding protein 2, AEBP2, Zinc finger protein AEBP2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100522805, 121536
Content And Storage:
-20°C
Form:
Liquid