50-173-6839
a-Synuclein Mouse anti-Human, Mouse, Rat, Clone: 1B10E9, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-6839-Each-of-1 | In Stock | ₹ 42,443.75 |
50-173-6839 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
a-Synuclein
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O55042, P37377, P37840
Gene Symbols
Snca
Immunogen
a-Synuclein Fusion Protein Ag1285
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
1B10E9
Conjugate
Unconjugated
Gene
SNCA
Gene Alias
Alpha synuclein, a-Synuclein, NACP, PARK1, PARK4, PD1, SNCA
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20617, 29219, 6622
Content And Storage
-20°C
Form
Liquid
Description
- This antibody can recognize all isoforms of alpha-syn
- Alpha-Synuclein belongs to the Synuclein family, which includes beta and gamma Synuclein, and is predomitly expressed in neurons, and concentrated at synaptic terminals
- Synucleins may be involved in the regulation of dopamine release and transport and the modulation of synaptic vesicle function
- Alpha-Synuclein is a small, presynaptic protein that is the major nonamyloid component of the pathological inclusions characteristic of a wide range of neurodegenerative disorders, collectively known as synucleinopathies
- Alpha-Synuclein is involved in the formation of SNARE complexes, and most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson′s disease (PD) and other neurodegenerative disorders
- Mutation of the alpha-synuclein gene is associated with familial forms of PD
- Alpha-Synuclein is known to reduce the fibrillization of the microtubule-associated protein, tau, to bind various targets such as 14-3-3, protein kinase C, synphilin-1, Elk and Tat-binding protein 1
- The alpha and beta synucleins are found primarily in brain tissue where they are seen mainly in neuronal cytosol and presynaptic terminals
- The antibody specific for alpha-synuclein does not cross react with beta-synuclein and will be useful for the confirmation of Parkinson′s disease and Lewy body dementia and other studies for the localization and detection of alpha-synuclein
- Four alternatively spliced transcripts that encode two different isoforms of the alpha-synuclein protein have been identified.
Compare Similar Items
Show Difference
Antigen: a-Synuclein
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O55042, P37377, P37840
Gene Symbols: Snca
Immunogen: a-Synuclein Fusion Protein Ag1285
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 1B10E9
Conjugate: Unconjugated
Gene: SNCA
Gene Alias: Alpha synuclein, a-Synuclein, NACP, PARK1, PARK4, PD1, SNCA
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20617, 29219, 6622
Content And Storage: -20°C
Form: Liquid
Antigen:
a-Synuclein
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O55042, P37377, P37840
Gene Symbols:
Snca
Immunogen:
a-Synuclein Fusion Protein Ag1285
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
1B10E9
Conjugate:
Unconjugated
Gene:
SNCA
Gene Alias:
Alpha synuclein, a-Synuclein, NACP, PARK1, PARK4, PD1, SNCA
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20617, 29219, 6622
Content And Storage:
-20°C
Form:
Liquid
Antigen: ZC3HAV1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q7Z2W4
Gene Symbols: ZC3HAV1
Immunogen: ZC3HAV1 Fusion Protein Ag10364
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 1G10B9
Conjugate: Unconjugated
Gene: ZC3HAV1
Gene Alias: FLB6421, ZAP, ZC3H2, ZC3HAV1, ZC3HDC2, Zinc finger antiviral protein
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 56829
Content And Storage: -20°C
Form: Liquid
Antigen:
ZC3HAV1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q7Z2W4
Gene Symbols:
ZC3HAV1
Immunogen:
ZC3HAV1 Fusion Protein Ag10364
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
1G10B9
Conjugate:
Unconjugated
Gene:
ZC3HAV1
Gene Alias:
FLB6421, ZAP, ZC3H2, ZC3HAV1, ZC3HDC2, Zinc finger antiviral protein
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
56829
Content And Storage:
-20°C
Form:
Liquid
Antigen: IkB alpha
Classification: Monoclonal
Concentration: 0.77 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P25963, Q63746, Q9Z1E3
Gene Symbols: Nfkbia
Immunogen: IkB alpha Fusion Protein Ag22040
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 2G6H7
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: I kappa B alpha, IkappaBalpha, IkB alpha, IKBA, MAD 3, MAD3, NF kappa B inhibitor alpha, NFKBI, NFKBIA
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 18035, 25493, 4792
Content And Storage: -20°C
Form: Liquid
Antigen:
IkB alpha
Classification:
Monoclonal
Concentration:
0.77 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P25963, Q63746, Q9Z1E3
Gene Symbols:
Nfkbia
Immunogen:
IkB alpha Fusion Protein Ag22040
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
2G6H7
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
I kappa B alpha, IkappaBalpha, IkB alpha, IKBA, MAD 3, MAD3, NF kappa B inhibitor alpha, NFKBI, NFKBIA
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
18035, 25493, 4792
Content And Storage:
-20°C
Form:
Liquid
Antigen: PDI
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P04785, P07237, P09103
Gene Symbols: P4hb
Immunogen: PDI Fusion Protein Ag1747
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 2E6A11
Conjugate: Unconjugated
Gene: P4HB
Gene Alias: DSI, ERBA2L, GIT, P4HB, P4Hbeta, p55, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, Protein disulfide isomerase
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 110255932, 18453, 25506, 5034
Content And Storage: -20°C
Form: Liquid
Antigen:
PDI
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P04785, P07237, P09103
Gene Symbols:
P4hb
Immunogen:
PDI Fusion Protein Ag1747
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
2E6A11
Conjugate:
Unconjugated
Gene:
P4HB
Gene Alias:
DSI, ERBA2L, GIT, P4HB, P4Hbeta, p55, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, Protein disulfide isomerase
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
110255932, 18453, 25506, 5034
Content And Storage:
-20°C
Form:
Liquid