50-173-6923

TAZ Mouse anti-Human, Mouse, Rat, Clone: 2A12A10, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-6923-Each-of-1 In Stock ₹ 42,443.75

50-173-6923 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

TAZ

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

Q9EPK5, Q9GZV5

Gene Symbols

Wwtr1

Immunogen

TAZ Fusion Protein Ag13330

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

2A12A10

Conjugate

Unconjugated

Gene

WWTR1

Gene Alias

TAZ, WWTR1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

25937, 295062, 97064

Content And Storage

-20°C

Form

Liquid

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Description

  • WW domain-containing transcription regulator protein 1 (WWTR1) is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor supression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1
  • In turn, MOB1 phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation
  • WWTR1 regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex
  • WWTR1 also regulates embryonic stem-cell self-renewal and promotes cell proliferation and epithelial-mesenchymal transition.

Compare Similar Items

Show Difference

Img

Proteintech Group Inc

50-173-6923

--


Antigen:
TAZ

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q9EPK5, Q9GZV5

Gene Symbols:
Wwtr1

Immunogen:
TAZ Fusion Protein Ag13330

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2A12A10

Conjugate:
Unconjugated

Gene:
WWTR1

Gene Alias:
TAZ, WWTR1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25937, 295062, 97064

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6927

--


Antigen:
MDH1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P14152, P40925

Gene Symbols:
Mdh1

Immunogen:
MDH1 Fusion Protein Ag8744

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
1F9A2

Conjugate:
Unconjugated

Gene:
MDH1

Gene Alias:
Cytosolic malate dehydrogenase, MDH s, MDH1, MDHA, MOR2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
17449, 4190

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6929

--


Antigen:
CNOT1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
A5YKK6

Gene Symbols:
CNOT1

Immunogen:
CNOT1 Fusion Protein Ag5623

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
1A10A11

Conjugate:
Unconjugated

Gene:
CNOT1

Gene Alias:
AD 005, CCR4 associated factor 1, CDC39, CNOT1, hNOT1, KIAA1007, NOT1, NOT1H

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
23019

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6930

--


Antigen:
SP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P08047

Gene Symbols:
SP1

Immunogen:
SP1 Fusion Protein Ag16720

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4G3H3

Conjugate:
Unconjugated

Gene:
SP1

Gene Alias:
SP1, Sp1 transcription factor, Transcription factor Sp1, TSFP1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6667

Content And Storage:
-20°C

Form:
Liquid