50-173-6936
USP7 Mouse anti-Human, Mouse, Rat, Clone: 3D7D11, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-6936-Each-of-1 | In Stock | ₹ 42,443.75 |
50-173-6936 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
USP7
Classification
Monoclonal
Concentration
0.77 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
Q4VSI4, Q6A4J8, Q93009
Gene Symbols
Usp7
Immunogen
USP7 Fusion Protein Ag25652
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
3D7D11
Conjugate
Unconjugated
Gene
USP7
Gene Alias
Deubiquitinating enzyme 7, HAUSP, TEF1, Ubiquitin thioesterase 7, USP7
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
252870, 360471, 7874
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
- Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP acitivity generally stabilizes its substrate proteins
- HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53.Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
- Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
- Another important role of HAUSP function involves the oncogenic stabilization of p53
- Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
- An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.
Compare Similar Items
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Antigen: USP7
Classification: Monoclonal
Concentration: 0.77 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: Q4VSI4, Q6A4J8, Q93009
Gene Symbols: Usp7
Immunogen: USP7 Fusion Protein Ag25652
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 3D7D11
Conjugate: Unconjugated
Gene: USP7
Gene Alias: Deubiquitinating enzyme 7, HAUSP, TEF1, Ubiquitin thioesterase 7, USP7
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 252870, 360471, 7874
Content And Storage: -20°C
Form: Liquid
Antigen:
USP7
Classification:
Monoclonal
Concentration:
0.77 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q4VSI4, Q6A4J8, Q93009
Gene Symbols:
Usp7
Immunogen:
USP7 Fusion Protein Ag25652
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
3D7D11
Conjugate:
Unconjugated
Gene:
USP7
Gene Alias:
Deubiquitinating enzyme 7, HAUSP, TEF1, Ubiquitin thioesterase 7, USP7
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
252870, 360471, 7874
Content And Storage:
-20°C
Form:
Liquid
Antigen: SMAD3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P84022, Q8BUN5
Gene Symbols: Smad3
Immunogen: Peptide
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 1F10B2
Conjugate: Unconjugated
Gene: SMAD3
Gene Alias: hMAD 3, hSMAD3, HSPC193, HsT17436, JV15 2, MAD homolog 3, Mad3, MADH3, Mothers against DPP homolog 3, SMAD 3, SMAD family member 3, SMAD3
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17127, 4088
Content And Storage: -20°C
Form: Liquid
Antigen:
SMAD3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P84022, Q8BUN5
Gene Symbols:
Smad3
Immunogen:
Peptide
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
1F10B2
Conjugate:
Unconjugated
Gene:
SMAD3
Gene Alias:
hMAD 3, hSMAD3, HSPC193, HsT17436, JV15 2, MAD homolog 3, Mad3, MADH3, Mothers against DPP homolog 3, SMAD 3, SMAD family member 3, SMAD3
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17127, 4088
Content And Storage:
-20°C
Form:
Liquid
Antigen: MKS1
Classification: Monoclonal
Concentration: 0.9 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: Q499Q5, Q9NXB0
Gene Symbols: Mks1
Immunogen: MKS1 Fusion Protein Ag9504
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Porcine, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 6A8B11
Conjugate: Unconjugated
Gene: MKS1
Gene Alias: BBS13, Meckel syndrome type 1 protein, Meckel syndrome, type 1, MES, MKS, MKS1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100514538, 287612, 54903
Content And Storage: -20°C
Form: Liquid
Antigen:
MKS1
Classification:
Monoclonal
Concentration:
0.9 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q499Q5, Q9NXB0
Gene Symbols:
Mks1
Immunogen:
MKS1 Fusion Protein Ag9504
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
6A8B11
Conjugate:
Unconjugated
Gene:
MKS1
Gene Alias:
BBS13, Meckel syndrome type 1 protein, Meckel syndrome, type 1, MES, MKS, MKS1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100514538, 287612, 54903
Content And Storage:
-20°C
Form:
Liquid
Antigen: CD11B/Integrin alpha M
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.: P11215
Gene Symbols: ITGAM
Immunogen: Peptide
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 1C7C2
Conjugate: Unconjugated
Gene: ITGAM
Gene Alias: CD11B, CR 3 alpha chain, CR3A, Integrin alpha M, ITGAM, MAC 1, MAC1A, MO1A, Neutrophil adherence receptor, SLEB6
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3684
Content And Storage: -20°C
Form: Liquid
Antigen:
CD11B/Integrin alpha M
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P11215
Gene Symbols:
ITGAM
Immunogen:
Peptide
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
1C7C2
Conjugate:
Unconjugated
Gene:
ITGAM
Gene Alias:
CD11B, CR 3 alpha chain, CR3A, Integrin alpha M, ITGAM, MAC 1, MAC1A, MO1A, Neutrophil adherence receptor, SLEB6
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3684
Content And Storage:
-20°C
Form:
Liquid