50-173-6992

GRP78/BIP Mouse anti-Human, Mouse, Rat, Clone: 1D6F7, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-6992-Each-of-1 In Stock ₹ 42,443.75

50-173-6992 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

GRP78/BIP

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P06761, P11021, P20029

Gene Symbols

HSPA5

Immunogen

GRP78/BIP Fusion Protein Ag2188

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

1D6F7

Conjugate

Unconjugated

Gene

HSPA5

Gene Alias

BIP, GRP 78, GRP78, Heat shock 70 kDa protein 5, HSPA5, MIF2

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

14828, 25617, 3309

Content And Storage

-20°C

Form

Liquid

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Description

  • Description GRP78 is a 78 kDa glucose regulated protein that belongs to the family of heat shock proteins that include HSP70
  • GRP78 is a resident protein of the endoplasmic reticulum (ER) and associates transiently with a variety of newly synthesized secretory and membrane proteins
  • GRP78 may also interact with mutant and misfolded proteins, marking them for degradation
  • The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C-terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP94) and protein disulfide isomerase (PDI)
  • The KDEL signal is recognized by the KDEL receptor and this interaction ensures recycling of escaped ER proteins back to the ER
  • GRP78′s involvement in correct folding of proteins and degradation of misfolded proteins is via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate
  • GRP78 is critical for maintece of cell homeostasis and the prevention of apoptosis
  • GRP78 protein levels have been shown to be a reliable biomarker of hypoglycemia and serves a neuroprotective function in neurons exposed to glutamate and oxidative stress
  • GRP78 levels are reduced in the brains of Alzheimer′s Disease patients, and decreased expression of GRP78 is found associated with missense mutations in the human presenilin-1 (PS1) gene
  • Further, the induction of the GRP78 protein has been associated with the development of drug-resistance to antitumor drugs.

Compare Similar Items

Show Difference

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Proteintech Group Inc

50-173-6992

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Antigen:
GRP78/BIP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P06761, P11021, P20029

Gene Symbols:
HSPA5

Immunogen:
GRP78/BIP Fusion Protein Ag2188

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
1D6F7

Conjugate:
Unconjugated

Gene:
HSPA5

Gene Alias:
BIP, GRP 78, GRP78, Heat shock 70 kDa protein 5, HSPA5, MIF2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14828, 25617, 3309

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6993

--


Antigen:
KAT2A/GNC5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q92830, Q9JHD2

Gene Symbols:
Kat2a

Immunogen:
KAT2A/GNC5 Fusion Protein Ag6940

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
1F6G7

Conjugate:
Unconjugated

Gene:
KAT2A

Gene Alias:
GCN5, GCN5L2, hGCN5, Histone acetyltransferase GCN5, HsGCN5, K(lysine) acetyltransferase 2A, KAT2A, Lysine acetyltransferase 2A, PCAF b, STAF97

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14534, 2648, 303539

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6994

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Antigen:
c-Cbl

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P22681

Gene Symbols:
CBL

Immunogen:
c-Cbl Fusion Protein Ag23033

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2F6D1

Conjugate:
Unconjugated

Gene:
CBL

Gene Alias:
C CBL, CBL, CBL2, c-Cbl, Proto oncogene c Cbl, RING finger protein 55, RNF55

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
867

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6995

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Antigen:
SLC9A9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q8BZ00, Q8IVB4

Gene Symbols:
Slc9a9

Immunogen:
SLC9A9 Fusion Protein Ag4660

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
1B8D9

Conjugate:
Unconjugated

Gene:
SLC9A9

Gene Alias:
Na(+)/H(+) exchanger 9, Nbla00118, NHE 9, NHE9, SLC9A9, Sodium/hydrogen exchanger 9

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
285195, 331004, 363115

Content And Storage:
-20°C

Form:
Liquid