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50-173-7064

EIF2AK2 Mouse anti-Human, Clone: 2A8A4, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-173-7064-Each-of-1 In Stock ₹ 42,443.75

50-173-7064 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

EIF2AK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P19525

Gene Symbols

EIF2AK2

Immunogen

EIF2AK2 Fusion Protein Ag13010

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

2A8A4

Conjugate

Unconjugated

Gene

EIF2AK2

Gene Alias

eIF 2A protein kinase 2, EIF2AK1, EIF2AK2, P1/eIF 2A protein kinase, p68 kinase, PKR, PRKR, Protein kinase RNA activated

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5610

Content And Storage

-20°C

Form

Liquid

Description

  • This antibody is specific to EIF2AK2
  • PKR is a 68 kDa protein and an IFN-induced serine/threonine protein kinase consisting of two N-terminal RNA-binding regulatory domains and a functional C-terminal serine/threonine protein kinase domain
  • Activated by dsRNA produced during viral infections, PKR plays a key role in IFN induced-innate antiviral response, virus-induced apoptosis, cell growth & differentiation
  • Upon activation, PKR gets autophosphorylated and catalyzes the phosphorylation of elF2 alpha subunit, which leads to an inhibition of protein synthesis
  • PKR induces apoptosis by up-regulating Fas expression and mediates FADD/Caspase-8 death signaling pathway
  • Upon viral infection, it functions as a dual protein, sequentially activating both cell survival & cell death pathways using kinase independent and dependent strategies
  • PRKR regulates multiple pathways which include NF-kappaB activation, p53, p38, & PDGF signaling pathway
  • PKR has been implicated in tumor suppression & maligcy
  • To evade the antiviral effects of PKR, viruses have evolved multiple mechanisms, such as the inhibition of PKR by the non-structural protein (NS1) of the influenza virus
  • More recently, PKR has been implicated in several neurodegenerative diseases including Alzheimer, Huntington, and amyotrophic lateral sclerosis.

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Proteintech Group Inc

50-173-7064

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Antigen:
EIF2AK2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P19525
Gene Symbols:
EIF2AK2
Immunogen:
EIF2AK2 Fusion Protein Ag13010
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
2A8A4
Conjugate:
Unconjugated
Gene:
EIF2AK2
Gene Alias:
eIF 2A protein kinase 2, EIF2AK1, EIF2AK2, P1/eIF 2A protein kinase, p68 kinase, PKR, PRKR, Protein kinase RNA activated
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5610
Content And Storage:
-20°C
Form:
Liquid

Img

Proteintech Group Inc

50-173-7065

--

Antigen:
RNF126
Classification:
Monoclonal
Concentration:
0.93 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q91YL2, Q9BV68
Gene Symbols:
Rnf126
Immunogen:
RNF126 Fusion Protein Ag13816
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
1E1B10
Conjugate:
Unconjugated
Gene:
RNF126
Gene Alias:
ring finger protein 126, RNF126
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
314613, 55658, 70294
Content And Storage:
-20°C
Form:
Liquid

Img

Proteintech Group Inc

50-173-7066

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Antigen:
RAB3GAP2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
Q9H2M9
Gene Symbols:
RAB3GAP2
Immunogen:
RAB3GAP2 Fusion Protein Ag20254
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
3A4A1
Conjugate:
Unconjugated
Gene:
RAB3GAP2
Gene Alias:
DKFZp434D245, FLJ14579, KIAA0839, p150, Rab3 GAP p150, Rab3 GAP regulatory subunit, RAB3 GAP150, RAB3GAP150, RAB3GAP2, RGAP iso
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
25782
Content And Storage:
-20°C
Form:
Liquid

Img

Proteintech Group Inc

50-173-7067

--

Antigen:
CEBPB
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.:
P17676, P21272
Gene Symbols:
CEBPB
Immunogen:
CEBPB Fusion Protein Ag20073
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
2B6E10
Conjugate:
Unconjugated
Gene:
CEBPB
Gene Alias:
C/EBP beta, CEBPB, CRP2, IL6DBP, LAP, Liver activator protein, NF IL6, Nuclear factor NF IL6, TCF 5, TCF5, Transcription factor 5
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
1051, 24253
Content And Storage:
-20°C
Form:
Liquid