CD11b Monoclonal Antibody (LM2/1), Biotin, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-177-16-Each | In Stock | ₹ 22,814.57 |
50-177-16 - Each
In Stock
Quantity
1
Base Price: ₹ 22,814.57
GST (18%): ₹ 4,106.623
Total Price: ₹ 26,921.193
Antigen
CD11b
Classification
Monoclonal
Concentration
10 μL/Test
Formulation
TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4
Gene Accession No.
P11215
Gene Symbols
ITGAM
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3684
Content And Storage
2-8°C
Form
Liquid
Applications
Flow Cytometry
Clone
LM2/1
Conjugate
Biotin
Gene
ITGAM
Gene Alias
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Description: Integrin alpha M (LM2/1) is a mouse monoclonal antibody raised against the Idomain of Integrin alpha M of human origin
- The antibody can be used to stain acetone-fixed cryostat sections or cell smears
- BMS104 is also suitable as primary antibody in staining for FACS analysis
- BMS104FI can be used for direct staining of cells
- BMS104BT can be used in a 2-step procedure using the biotin-(strept)avidin system
- BMS104 shows minor blocking effects of Mac-1alpha function
- Applications Tested: Flow Cytometry
- Purity: >95%
- CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18)
- The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3)
- CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain
- CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions
- CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue
- The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages
- Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages
- Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.
Compare Similar Items
Show Difference
Antigen: CD11b
Classification: Monoclonal
Concentration: 10 μL/Test
Formulation: TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4
Gene Accession No.: P11215
Gene Symbols: ITGAM
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3684
Content And Storage: 2-8°C
Form: Liquid
Applications: Flow Cytometry
Clone: LM2/1
Conjugate: Biotin
Gene: ITGAM
Gene Alias: antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
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