50-194-3836

beta Amyloid Polyclonal Antibody, Rockland™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-194-3836-Each-of-1 In Stock ₹ 48,259.26

50-194-3836 - Each of 1

₹ 48,259.26

In Stock

Quantity

1

Base Price: ₹ 48,259.26

GST (18%): ₹ 8,686.667

Total Price: ₹ 56,945.927

Antigen

beta Amyloid

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APP

Gene Alias

A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; Alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid ß; Amyloid-beta A4 protein; Amyloid-beta precursor protein; amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C9

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

11820, 351

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

P05067, P12023

Gene Symbols

APP

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This affinity-purified antibody is directed against the amino terminal end of beta amyloid and is useful in determining its presence in various assays
  • Polyclonal anti-beta amyloid detects human and mouse beta amyloid
  • Cross reactivity with beta amyloid from other species is likely but has not been determined
  • Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease
  • Abeta peptide is 40-43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process
  • The first step involves cleavage of the extracellular, amino-terminal domain of beta APP
  • Protein cleavage is performed by an aspartyl protease, beta-secretase (BACE) which is synthesized as a propeptide and must be modified to the mature and active form by the prohormone convertase, furin
  • Beta APP cleavage by the mature form of BACE results in the cellular secretion of a segment of beta APP, and a membrane-bound remnant
  • The remnant protein is processed by another protease, gamma-secretase
  • Gamma-secretase cleaves an intra-membrane site in the carboxyl-terminal domain of beta APP, thus generating the amyloid beta peptide
  • Gamma-secretase is believed to be a multi-subunit complex containing presenilin-1 and 2 as central components
  • The transmembrane glycoprotein, nicastrin, is associated with presinilins and has been found to bind to the carboxyl-terminus of beta APP and helps to modulate the production of the amyloid beta peptide
  • Abeta is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles
  • Alzheimer’s disease, the most common cause of senile dementia, is characterized by abnormal filamentous protein deposits in the brain
  • Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type), cerebroarterial amyloidosis (cerebral amyloid angiopathy) and in the Guam Parkinson-Dementia complex.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-194-3836

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Antigen:
beta Amyloid

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APP

Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; Alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid ß; Amyloid-beta A4 protein; Amyloid-beta precursor protein; amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C9

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
11820, 351

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P05067, P12023

Gene Symbols:
APP

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Img

Rockland Immunochemicals

50-194-3837

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Antigen:
Phospho-NFkB (Ser276)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RELA

Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; BOS_24973; EBP-1; I79_021812; MGC131774; NFkappaB p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NFKB1; Nfkb3; NFkB-p50; nuclear factor kappa B subunit p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; Putative transcription factor p65 homolog; rel1; Rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; XRel1; xrela

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
5970

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q04206

Gene Symbols:
RELA

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Rockland Immunochemicals

50-194-3838

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Antigen:
Human Haptoglobin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HP

Gene Alias:
Ba1-647; binding peptide; BP; Haptoglobin; haptoglobin alpha 1S; Haptoglobin alpha chain; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; Haptoglobin beta chain; haptoglobin, alpha polypeptide; haptoglobin, beta polypeptide; haptoglobin-like; haptoglobin-related protein; HP; HP-1; HP2ALPHA2; HP2-ALPHA-2; HPA1S; HPR; HPT; Liver regeneration-related protein LRRG173; LOC479668; MGC111141; MGC133752; preHP2; Zonulin

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
3240

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
2.5 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P00738

Gene Symbols:
HP

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Rockland Immunochemicals

50-194-3839

--


Antigen:
RFP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
RFP tag

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
0.02M potassium phosphate with 0.01% BSA, 0.15M NaCl, 25% glycerol and 0.01% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody