50-197-9838
FGFR1 Mouse anti-Human, Clone: 4C3, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-197-9838-Each-of-1 | In Stock | ₹ 43,507.26 |
50-197-9838 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,507.26
GST (18%): ₹ 7,831.307
Total Price: ₹ 51,338.567
Antigen
FGFR1
Classification
Monoclonal
Concentration
1 μg/mL
Formulation
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.
P11362
Gene Symbols
FGFR1
Immunogen
This FGFR1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 806-842 amino acids from the C-terminal region of human FGFR1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
4C3
Conjugate
Unconjugated
Gene
FGFR1
Gene Alias
2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R; bFGF-R-1; BOS_23880; CD331; CD331 antigen; CEK; CEK1; cek1 protein; c-fgr; Eask; ECCL; FGF receptor-1; FGFBR; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); Flg; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; MFR; N-sam; OGD; Proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2260
Content And Storage
-20°C
Form
Liquid
Description
- FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig-like domain and a tyrosine kinase domain
- FGFR1 has multiple isoforms and is a Type I membrane protein
- FGFR family members differ from one another in their ligand affinities and tissue distribution
- A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain
- The extracellular portion of FGFR1 interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation
- FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction
- FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform
- FGFR1 has been shown to interact with N-cadherin and NCAM
- Four genes encoding for high affinity cell surface FGF receptors (FGFRs) have been identified: FGFR-1, FGFR-2, FGFR-3 and FGFR-4.FGFRs are members of the tyrosine kinase family of growth factor receptors
- At the mRNA level, FGFR1 is highly expressed in developing human tissues including the brain, vascular basement membrane and skin
- Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis
- Other defects in FGFR1 are responsible for several diseases which include Pfeiffer syndrome (PS), idiopathic hypogonadotropic hypogonadism (IHH), Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), non-syndromic trigonocephaly, Jackson-Weiss syndrome, Antley-Bixler syndrome
- Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
Compare Similar Items
Show Difference
Antigen: FGFR1
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P11362
Gene Symbols: FGFR1
Immunogen: This FGFR1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 806-842 amino acids from the C-terminal region of human FGFR1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 4C3
Conjugate: Unconjugated
Gene: FGFR1
Gene Alias: 2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R; bFGF-R-1; BOS_23880; CD331; CD331 antigen; CEK; CEK1; cek1 protein; c-fgr; Eask; ECCL; FGF receptor-1; FGFBR; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); Flg; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; MFR; N-sam; OGD; Proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 2260
Content And Storage: -20°C
Form: Liquid
Antigen:
FGFR1
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P11362
Gene Symbols:
FGFR1
Immunogen:
This FGFR1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 806-842 amino acids from the C-terminal region of human FGFR1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
4C3
Conjugate:
Unconjugated
Gene:
FGFR1
Gene Alias:
2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R; bFGF-R-1; BOS_23880; CD331; CD331 antigen; CEK; CEK1; cek1 protein; c-fgr; Eask; ECCL; FGF receptor-1; FGFBR; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); Flg; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; MFR; N-sam; OGD; Proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
2260
Content And Storage:
-20°C
Form:
Liquid
Antigen: Tyro3
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: Q06418
Gene Symbols: TYRO3
Immunogen: This Tyro3 antibody is generated from a mouse immunized with a recombinant protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Western Blot
Clone: 5A3
Conjugate: Unconjugated
Gene: TYRO3
Gene Alias: AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; Dtk; Etk-2; Etk2/tyro3; FLJ16467; Rek; RSE; SKY; soluble tyro 3; soluble tyro3; styro 3; styro3; Tif; TK19-2; tyro 3; TYRO3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; Tyrosine-protein kinase BYK; Tyrosine-protein kinase DTK; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 7301
Content And Storage: -20°C
Form: Liquid
Antigen:
Tyro3
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
Q06418
Gene Symbols:
TYRO3
Immunogen:
This Tyro3 antibody is generated from a mouse immunized with a recombinant protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
5A3
Conjugate:
Unconjugated
Gene:
TYRO3
Gene Alias:
AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; Dtk; Etk-2; Etk2/tyro3; FLJ16467; Rek; RSE; SKY; soluble tyro 3; soluble tyro3; styro 3; styro3; Tif; TK19-2; tyro 3; TYRO3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; Tyrosine-protein kinase BYK; Tyrosine-protein kinase DTK; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
7301
Content And Storage:
-20°C
Form:
Liquid
Antigen: NTRK2
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: Q16620
Gene Symbols: Ntrk2
Immunogen: This NTRK2 antibody is generated from a mouse immunized with a recombinant protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 14C9
Conjugate: Unconjugated
Gene: Ntrk2
Gene Alias: AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; Neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; Trkb; Trk-B; TrkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4915
Content And Storage: -20°C
Form: Liquid
Antigen:
NTRK2
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
Q16620
Gene Symbols:
Ntrk2
Immunogen:
This NTRK2 antibody is generated from a mouse immunized with a recombinant protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
14C9
Conjugate:
Unconjugated
Gene:
Ntrk2
Gene Alias:
AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; Neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; Trkb; Trk-B; TrkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4915
Content And Storage:
-20°C
Form:
Liquid
Antigen: LAMP1
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P11279
Gene Symbols: LAMP1
Immunogen: This LAMP1 antibody is generated from a mouse immunized with a recombinant protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 3C3
Conjugate: Unconjugated
Gene: LAMP1
Gene Alias: 120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; Lamp-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; Lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; Lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); Lysosome-associated membrane protein 1; P2B
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3916
Content And Storage: -20°C
Form: Liquid
Antigen:
LAMP1
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P11279
Gene Symbols:
LAMP1
Immunogen:
This LAMP1 antibody is generated from a mouse immunized with a recombinant protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
3C3
Conjugate:
Unconjugated
Gene:
LAMP1
Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; Lamp-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; Lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; Lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); Lysosome-associated membrane protein 1; P2B
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3916
Content And Storage:
-20°C
Form:
Liquid