50-197-9844

IRF3 Mouse anti-Human, Clone: 2C4, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-197-9844-Each-of-1 In Stock ₹ 43,507.26

50-197-9844 - Each of 1

₹ 43,507.26

In Stock

Quantity

1

Base Price: ₹ 43,507.26

GST (18%): ₹ 7,831.307

Total Price: ₹ 51,338.567

Antigen

IRF3

Classification

Monoclonal

Concentration

1 μg/mL

Formulation

TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.

Q14653

Gene Symbols

IRF3

Immunogen

This IRF3 antibody is generated from a mouse immunized with a recombinant protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

2C4

Conjugate

Unconjugated

Gene

IRF3

Gene Alias

C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3661

Content And Storage

-20°C

Form

Liquid

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Description

  • IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
  • It plays a critical role in the innate immune response against DNA and RNA viruses
  • IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
  • It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
  • IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
  • It is phosphorylated by IKBKE and TBK1 kinases
  • This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
  • Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.

Compare Similar Items

Show Difference

Img

Bioss

50-197-9844

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Antigen:
IRF3

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
Q14653

Gene Symbols:
IRF3

Immunogen:
This IRF3 antibody is generated from a mouse immunized with a recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
2C4

Conjugate:
Unconjugated

Gene:
IRF3

Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3661

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-197-9845

--


Antigen:
RAB3B

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P20337

Gene Symbols:
Rab3b

Immunogen:
This RAB3B antibody is generated from a mouse immunized with a recombinant protein of human RAB3B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
7F5

Conjugate:
Unconjugated

Gene:
Rab3b

Gene Alias:
2610528C18Rik; brain antigen RAB3B; RAB3B; RAB3B, member RAS oncogene family; Ras-related protein Rab-3B

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5865

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-197-9846

--


Antigen:
TIMP2

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P16035

Gene Symbols:
TIMP2

Immunogen:
This TIMP2 antibody is generated from a mouse immunized with arecombinant protein of human TIMP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
4C7

Conjugate:
Unconjugated

Gene:
TIMP2

Gene Alias:
BOS_19535; Collagenase inhibitor; CSC-21K; D11Bwg1104e; DDC8; Metalloproteinase inhibitor 2; metalloproteinase inhibitor TIMP-2; testicular secretory protein Li 57; TIMP metallopeptidase inhibitor 2; Timp2; Timp-2; tissue inhibitor of matrix metalloproteinase-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinase-2; Tissue inhibitor of metalloproteinases 2; tissue inhibitor of mettaloproteinase 2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7077

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-197-9847

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Antigen:
S100A2

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P29034

Gene Symbols:
S100A2

Immunogen:
This S100A2 antibody is generated from a mouse immunized with a recombinant protein of human S100A2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
2C1

Conjugate:
Unconjugated

Gene:
S100A2

Gene Alias:
CAN19; EG628324; predicted gene, EG628324; Protein S100-A2; Protein S-100L; S100 calcium binding protein A2; S100 calcium-binding protein A2; S100A2; S100L

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6273

Content And Storage:
-20°C

Form:
Liquid