50-197-9883

BCL-2 Mouse anti-Human, Clone: 1A5, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-197-9883-Each-of-1 In Stock ₹ 45,440.92

50-197-9883 - Each of 1

₹ 45,440.92

In Stock

Quantity

1

Base Price: ₹ 45,440.92

GST (18%): ₹ 8,179.366

Total Price: ₹ 53,620.286

Antigen

BCL-2

Classification

Monoclonal

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P10415

Gene Symbols

Bcl2

Immunogen

Recombinant protein fragment (1-220 amino acids range) of human Bcl-2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

1A5

Conjugate

Unconjugated

Gene

Bcl2

Gene Alias

Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

596

Content And Storage

-20°C

Form

Liquid

Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

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Bioss

50-197-9883

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Antigen:
BCL-2

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
Recombinant protein fragment (1-220 amino acids range) of human Bcl-2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
1A5

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-197-9884

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Antigen:
TIMP-1

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P01033

Gene Symbols:
TIMP1

Immunogen:
Recombinant human TIMP-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
4C2

Conjugate:
Unconjugated

Gene:
TIMP1

Gene Alias:
BOS_25915; CLGI; Collagenase inhibitor; Collagenase inhibitor 16C8 fibroblast; EG-1; Embryogenin-1; EPA; EPO; erythroid potentiating activity; Erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; HCI; LOC100009047; Metalloproteinase inhibitor; Metalloproteinase inhibitor 1; metalloproteinase tissue inhibitor; metalloproteinase tissue inhibitor 1; MMP inhibitor; RP1-230G1.3; Timp; TIMP 1; TIMP metallopeptidase inhibitor 1; TIMP1; Timp-1; tissue inhibitor of matrix metalloproteinase-1; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); tissue inhibitor of metalloproteinase-1; Tissue inhibitor of metalloproteinases 1; TPA-induced protein; TPA-S1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7076

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-197-9886

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Antigen:
AFP

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P02771

Gene Symbols:
AFP

Immunogen:
Full length human AFP protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
A2

Conjugate:
Unconjugated

Gene:
AFP

Gene Alias:
a fetoglobulin; a fetoprotein; AFP; AFPD; alpha fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin; Alpha-fetoprotein; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
174

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-197-9888

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Antigen:
CEA

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P06731

Gene Symbols:
Ceacam5

Immunogen:
Human Carcinoembryonic Antigen.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
C3

Conjugate:
Unconjugated

Gene:
Ceacam5

Gene Alias:
1600029H12Rik; Carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CEA; CEACAM5; Meconium antigen 100; OTTHUMP00000199033; Pregnancy-specific glycoprotein 30; Psg30; sCD66e; soluble CD66e

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1048

Content And Storage:
-20°C

Form:
Liquid